Deoxycorticosterone Producing Tumor as a Cause of Resistant Hypertension

We describe a young woman with longstanding resistant hypertension. Evaluation for renal artery stenosis and primary aldosteronism was unrevealing. In this setting of a suppressed plasma aldosterone concentration (PAC) and a suppressed plasma renin activity (PRA), a differential diagnosis of a deoxy...

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Main Authors: Saurabh Gupta, Jose Melendez, Apurv Khanna
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2010/372719
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author Saurabh Gupta
Jose Melendez
Apurv Khanna
author_facet Saurabh Gupta
Jose Melendez
Apurv Khanna
author_sort Saurabh Gupta
collection DOAJ
description We describe a young woman with longstanding resistant hypertension. Evaluation for renal artery stenosis and primary aldosteronism was unrevealing. In this setting of a suppressed plasma aldosterone concentration (PAC) and a suppressed plasma renin activity (PRA), a differential diagnosis of a deoxycorticosterone (DOC) producing tumor was entertained. Biochemical and imaging studies confirmed this diagnosis. Rare and novel DOC producing tumors are an important cause of resistant hypertension.
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spelling doaj-art-9088cc20345045f2b2e915464aba42c32025-02-03T01:10:05ZengWileyCase Reports in Medicine1687-96271687-96352010-01-01201010.1155/2010/372719372719Deoxycorticosterone Producing Tumor as a Cause of Resistant HypertensionSaurabh Gupta0Jose Melendez1Apurv Khanna2Department of Medicine, University of Connecticut Health Center, Farmington, CT 06030, USADepartment of Medicine, University of Connecticut Health Center, Farmington, CT 06030, USADepartment of Medicine, Division of Nephrology, SUNY Upstate Medical University, Syracuse, NY 13210, USAWe describe a young woman with longstanding resistant hypertension. Evaluation for renal artery stenosis and primary aldosteronism was unrevealing. In this setting of a suppressed plasma aldosterone concentration (PAC) and a suppressed plasma renin activity (PRA), a differential diagnosis of a deoxycorticosterone (DOC) producing tumor was entertained. Biochemical and imaging studies confirmed this diagnosis. Rare and novel DOC producing tumors are an important cause of resistant hypertension.http://dx.doi.org/10.1155/2010/372719
spellingShingle Saurabh Gupta
Jose Melendez
Apurv Khanna
Deoxycorticosterone Producing Tumor as a Cause of Resistant Hypertension
Case Reports in Medicine
title Deoxycorticosterone Producing Tumor as a Cause of Resistant Hypertension
title_full Deoxycorticosterone Producing Tumor as a Cause of Resistant Hypertension
title_fullStr Deoxycorticosterone Producing Tumor as a Cause of Resistant Hypertension
title_full_unstemmed Deoxycorticosterone Producing Tumor as a Cause of Resistant Hypertension
title_short Deoxycorticosterone Producing Tumor as a Cause of Resistant Hypertension
title_sort deoxycorticosterone producing tumor as a cause of resistant hypertension
url http://dx.doi.org/10.1155/2010/372719
work_keys_str_mv AT saurabhgupta deoxycorticosteroneproducingtumorasacauseofresistanthypertension
AT josemelendez deoxycorticosteroneproducingtumorasacauseofresistanthypertension
AT apurvkhanna deoxycorticosteroneproducingtumorasacauseofresistanthypertension