Topographic Mapping of Collagenous Gastritis

A 74-year-old woman was investigated for abdominal pain and diarrhea. Endoscopic examinations including biopsies of the stomach and colon demonstrated the typical subepithelial deposits characteristic of collagenous gastritis and collagenous colitis. Histochemical and ultrastructural methods confirm...

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Main Author: Hugh J Freeman
Format: Article
Language:English
Published: Wiley 2001-01-01
Series:Canadian Journal of Gastroenterology
Online Access:http://dx.doi.org/10.1155/2001/243198
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author Hugh J Freeman
author_facet Hugh J Freeman
author_sort Hugh J Freeman
collection DOAJ
description A 74-year-old woman was investigated for abdominal pain and diarrhea. Endoscopic examinations including biopsies of the stomach and colon demonstrated the typical subepithelial deposits characteristic of collagenous gastritis and collagenous colitis. Histochemical and ultrastructural methods confirmed the presence of collagen in the subepithelial deposits. The topographic distribution of these collagen deposits and their relationship to the inflammatory process in the stomach were then defined by endoscopic mapping and multiple site biopsies of the mucosa in the gastric body and antrum. These studies indicate that collagenous gastritis not only is distinctive, but also is a far more extensive and diffuse inflammatory process than has previously been appreciated.
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spelling doaj-art-9062ed2388684bad80cf699bf0e428f92025-02-03T06:44:40ZengWileyCanadian Journal of Gastroenterology0835-79002001-01-0115747547810.1155/2001/243198Topographic Mapping of Collagenous GastritisHugh J Freeman0Department of Medicine (Gastroenterology), University of British Columbia, Vancouver, British Columbia, CanadaA 74-year-old woman was investigated for abdominal pain and diarrhea. Endoscopic examinations including biopsies of the stomach and colon demonstrated the typical subepithelial deposits characteristic of collagenous gastritis and collagenous colitis. Histochemical and ultrastructural methods confirmed the presence of collagen in the subepithelial deposits. The topographic distribution of these collagen deposits and their relationship to the inflammatory process in the stomach were then defined by endoscopic mapping and multiple site biopsies of the mucosa in the gastric body and antrum. These studies indicate that collagenous gastritis not only is distinctive, but also is a far more extensive and diffuse inflammatory process than has previously been appreciated.http://dx.doi.org/10.1155/2001/243198
spellingShingle Hugh J Freeman
Topographic Mapping of Collagenous Gastritis
Canadian Journal of Gastroenterology
title Topographic Mapping of Collagenous Gastritis
title_full Topographic Mapping of Collagenous Gastritis
title_fullStr Topographic Mapping of Collagenous Gastritis
title_full_unstemmed Topographic Mapping of Collagenous Gastritis
title_short Topographic Mapping of Collagenous Gastritis
title_sort topographic mapping of collagenous gastritis
url http://dx.doi.org/10.1155/2001/243198
work_keys_str_mv AT hughjfreeman topographicmappingofcollagenousgastritis