Early stage prediction of bone regeneration using FEA and cell differentiation algorithms with 3D-printed PLA and PCL scaffolds: modeling and application to dorsal double-plating in distal radius fractures

Early stage prediction of bone regeneration using FEA and cell differentiation algorithms with 3D-printed PLA and PCL scaffolds: modeling and application to dorsal double-plating in distal radius fractures

Abstract This study introduces an advanced framework that integrates biphasic cell differentiation bone remodeling theory with finite element (FE) analysis and multi-remodeling simulation to evaluate the performance of 3D-printed biodegradable scaffolds for bone defect repair. The program incorporat...

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Bibliographic Details
Main Authors: Hsuan Chih Liu, Ya-Han Chan, Shao-Fu Huang, Wei-Che Tsai, Yen Cheng, Chun-Li Lin
Format: Article
Language:English
Published: BMC 2025-06-01
Series:3D Printing in Medicine
Subjects:
Bone remodeling
3D printing
PLA/PCL
Biomechanical
Scaffold
Lattice
Online Access:https://doi.org/10.1186/s41205-025-00278-7
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