SEMA3B switches axon-axon to axon-glia interactions required for unmyelinated axon envelopment and integrity

SEMA3B switches axon-axon to axon-glia interactions required for unmyelinated axon envelopment and integrity

Abstract During peripheral nerve (PN) development, unmyelinated axons (nmAs) tightly fasciculate before being separated and enveloped by non-myelinating Schwann cells (nmSCs), glial cells essential for maintaining nmA integrity. How such a switch from axon-axon to axon-glia interactions is achieved...

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Bibliographic Details
Main Authors: Li Liu, Zhigang Gao, Xueyuan Niu, Hong Yu, Xiaolong Xin, Yanlan Gu, Genghai Ma, Yan Gu, Yijun Liu, Sanhua Fang, Till Marquardt, Liang Wang
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-61318-8
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