Leptin Deficiency and Its Effects on Tibial and Vertebral Bone Mechanical Properties in Mature Genetically Lean and Obese JCR:LA-Corpulent Rats
Leptin signaling deficient rodents have emerged as models of obesity/insulin resistance syndrome. Altered leptin signaling, however, can affect axial and appendicular bone geometrical properties differently, and, thus, we hypothesized that leptin-deficiency would differentially influence mechanical...
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Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2012-01-01
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Series: | Journal of Obesity |
Online Access: | http://dx.doi.org/10.1155/2012/650193 |
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