Acute Liver Failure Occurring during the First Trimester of Pregnancy Successfully Treated with Living Donor Liver Transplantation
Acute liver failure (ALF) during pregnancy remains difficult to treat, and despite advances in treatment, liver transplantation must be selected as treatment option in certain cases. We report a 30-year-old woman with ALF of unknown etiology, occurring during the first trimester of pregnancy. Her co...
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| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Case Reports in Transplantation |
| Online Access: | http://dx.doi.org/10.1155/2013/309545 |
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| author | Naoya Kanogawa Tatsuo Kanda Masayuki Ohtsuka Masato Nakamura Tatsuo Miyamura Shin Yasui Makoto Arai Hitoshi Maruyama Keiichi Fujiwara Makio Shozu Shigeto Oda Masaru Miyazaki Osamu Yokosuka |
| author_facet | Naoya Kanogawa Tatsuo Kanda Masayuki Ohtsuka Masato Nakamura Tatsuo Miyamura Shin Yasui Makoto Arai Hitoshi Maruyama Keiichi Fujiwara Makio Shozu Shigeto Oda Masaru Miyazaki Osamu Yokosuka |
| author_sort | Naoya Kanogawa |
| collection | DOAJ |
| description | Acute liver failure (ALF) during pregnancy remains difficult to treat, and despite advances in treatment, liver transplantation must be selected as treatment option in certain cases. We report a 30-year-old woman with ALF of unknown etiology, occurring during the first trimester of pregnancy. Her condition was complicated by consciousness disturbance and coagulopathy due to ALF, but she was successfully treated with living donor liver transplantation 7 days after dilatation and curettage. At 9-month followup, she was in good medical condition. Liver transplantation has been reported as one of the treatment options for ALF during pregnancy with the prognosis varying depending on the trimester, from living donor or deceased donor liver transplantation. Of importance is that clinicians always think of emergent liver transplantation as a therapeutic option in ALF even in the first trimester of pregnancy. |
| format | Article |
| id | doaj-art-8fc1110f1c434cdc8ebfe0d0f0564924 |
| institution | Kabale University |
| issn | 2090-6943 2090-6951 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Transplantation |
| spelling | doaj-art-8fc1110f1c434cdc8ebfe0d0f05649242025-02-03T01:11:22ZengWileyCase Reports in Transplantation2090-69432090-69512013-01-01201310.1155/2013/309545309545Acute Liver Failure Occurring during the First Trimester of Pregnancy Successfully Treated with Living Donor Liver TransplantationNaoya Kanogawa0Tatsuo Kanda1Masayuki Ohtsuka2Masato Nakamura3Tatsuo Miyamura4Shin Yasui5Makoto Arai6Hitoshi Maruyama7Keiichi Fujiwara8Makio Shozu9Shigeto Oda10Masaru Miyazaki11Osamu Yokosuka12Department of Gastroenterology and Nephrology, Chiba University, Graduate School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba 260-8677, JapanDepartment of Gastroenterology and Nephrology, Chiba University, Graduate School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba 260-8677, JapanDepartment of General Surgery, Chiba University, Graduate School of Medicine, Chuo-ku, Chiba 260-8677, JapanDepartment of Gastroenterology and Nephrology, Chiba University, Graduate School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba 260-8677, JapanDepartment of Gastroenterology and Nephrology, Chiba University, Graduate School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba 260-8677, JapanDepartment of Gastroenterology and Nephrology, Chiba University, Graduate School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba 260-8677, JapanDepartment of Gastroenterology and Nephrology, Chiba University, Graduate School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba 260-8677, JapanDepartment of Gastroenterology and Nephrology, Chiba University, Graduate School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba 260-8677, JapanDepartment of Gastroenterology and Nephrology, Chiba University, Graduate School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba 260-8677, JapanDepartment of Reproductive Medicine, Chiba University, Graduate School of Medicine, Chuo-ku, Chiba 260-8677, JapanDepartment of Emergency and Critical Care Medicine, Chiba University, Graduate School of Medicine, Chuo-ku, Chiba 260-8677, JapanDepartment of General Surgery, Chiba University, Graduate School of Medicine, Chuo-ku, Chiba 260-8677, JapanDepartment of Gastroenterology and Nephrology, Chiba University, Graduate School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba 260-8677, JapanAcute liver failure (ALF) during pregnancy remains difficult to treat, and despite advances in treatment, liver transplantation must be selected as treatment option in certain cases. We report a 30-year-old woman with ALF of unknown etiology, occurring during the first trimester of pregnancy. Her condition was complicated by consciousness disturbance and coagulopathy due to ALF, but she was successfully treated with living donor liver transplantation 7 days after dilatation and curettage. At 9-month followup, she was in good medical condition. Liver transplantation has been reported as one of the treatment options for ALF during pregnancy with the prognosis varying depending on the trimester, from living donor or deceased donor liver transplantation. Of importance is that clinicians always think of emergent liver transplantation as a therapeutic option in ALF even in the first trimester of pregnancy.http://dx.doi.org/10.1155/2013/309545 |
| spellingShingle | Naoya Kanogawa Tatsuo Kanda Masayuki Ohtsuka Masato Nakamura Tatsuo Miyamura Shin Yasui Makoto Arai Hitoshi Maruyama Keiichi Fujiwara Makio Shozu Shigeto Oda Masaru Miyazaki Osamu Yokosuka Acute Liver Failure Occurring during the First Trimester of Pregnancy Successfully Treated with Living Donor Liver Transplantation Case Reports in Transplantation |
| title | Acute Liver Failure Occurring during the First Trimester of Pregnancy Successfully Treated with Living Donor Liver Transplantation |
| title_full | Acute Liver Failure Occurring during the First Trimester of Pregnancy Successfully Treated with Living Donor Liver Transplantation |
| title_fullStr | Acute Liver Failure Occurring during the First Trimester of Pregnancy Successfully Treated with Living Donor Liver Transplantation |
| title_full_unstemmed | Acute Liver Failure Occurring during the First Trimester of Pregnancy Successfully Treated with Living Donor Liver Transplantation |
| title_short | Acute Liver Failure Occurring during the First Trimester of Pregnancy Successfully Treated with Living Donor Liver Transplantation |
| title_sort | acute liver failure occurring during the first trimester of pregnancy successfully treated with living donor liver transplantation |
| url | http://dx.doi.org/10.1155/2013/309545 |
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