Ferroptosis in Pulmonary Disease and Lung Cancer: Molecular Mechanisms, Crosstalk Regulation, and Therapeutic Strategies

Ferroptosis in Pulmonary Disease and Lung Cancer: Molecular Mechanisms, Crosstalk Regulation, and Therapeutic Strategies

ABSTRACT Ferroptosis is a distinct form of iron‐dependent programmed cell death characterized primarily by intracellular iron accumulation and lipid peroxidation. Multiple cellular processes, including amino acid metabolism, iron metabolism, lipid metabolism, various signaling pathways, and autophag...

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Main Authors: Dandan Guo, Songhua Cai, Lvdan Deng, Wangting Xu, Sentao Fu, Yaling Lin, Tong Jiang, Qing Li, Zhijun Shen, Jian Zhang, Peng Luo, Bufu Tang, Ling Wang
Format: Article
Language:English
Published: Wiley 2025-03-01
Series:MedComm
Subjects:
ferroptosis
immune microenvironment
lung cancer
molecular mechanisms
pulmonary disease
Online Access:https://doi.org/10.1002/mco2.70116
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