Paclitaxel, interferons and functional reprogramming of tumor-associated macrophages in optimized chemo-immunotherapy

Immune checkpoint inhibition (ICI) targeting programmed cell death protein-1 (PD1) prevents the elimination of activated cytotoxic T lymphocytes (CTLs) by programmed death-ligand 1/2-expressing cancer and myeloid cells in the tumor microenvironment (TME). ICI has shown its effectiveness in many soli...

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Bibliographic Details
Main Authors: Pawel Kalinski, Kathleen M Kokolus, Shipra Gandhi
Format: Article
Language:English
Published: BMJ Publishing Group 2025-05-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/13/5/e010960.full
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