Epigenetic changes and serotype-specific responses of alveolar type II epithelial cells to Streptococcus pneumoniae in resolving influenza A virus infection

Epigenetic changes and serotype-specific responses of alveolar type II epithelial cells to Streptococcus pneumoniae in resolving influenza A virus infection

Abstract Background Pneumococcal pneumonia following influenza A virus (IAV) infection is a synergistic complication with high mortality in which IAV infection modulates host antibacterial responses and affects bacterial invasiveness of Streptococcus pneumoniae (S. pn.). IAV-mediated effects can las...

Full description

Saved in:
Bibliographic Details
Main Authors: Julia D Boehme, Andreas Jeron, Kristin Schultz, Lars Melcher, Katharina Schott, Elif Gelmez, Andrea Kröger, Sabine Stegemann-Koniszewski, Dunja Bruder
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Cell Communication and Signaling
Subjects:
Influenza A virus
Streptococcus pneumoniae
Alveolar type II epithelial cells
Interferon response
Secondary infection
Gene co-expression network
Online Access:https://doi.org/10.1186/s12964-025-02284-y
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items