Change of TGF-β1 Gene Expression and TGF-β1 Protein Level in Gingival Crevicular Fluid and Identification of Plaque Bacteria in a Patient with Recurrent Localized Gingival Enlargement before and after Gingivectomy

This case report highlights the change of TGF-β1 gene expressions and TGF-β1 protein level in gingival crevicular fluid (GCF) and identification of plaque bacteria in a patient with recurrent localized gingival enlargement before and after gingivectomy treatment. A 26-year-old woman came to AG Denta...

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Main Authors: Lilies Anggarwati Astuti, Mochammad Hatta, Sri Oktawati, Rosdiana Natzir, Ressy Dwiyanti
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Case Reports in Dentistry
Online Access:http://dx.doi.org/10.1155/2018/3670583
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author Lilies Anggarwati Astuti
Mochammad Hatta
Sri Oktawati
Rosdiana Natzir
Ressy Dwiyanti
author_facet Lilies Anggarwati Astuti
Mochammad Hatta
Sri Oktawati
Rosdiana Natzir
Ressy Dwiyanti
author_sort Lilies Anggarwati Astuti
collection DOAJ
description This case report highlights the change of TGF-β1 gene expressions and TGF-β1 protein level in gingival crevicular fluid (GCF) and identification of plaque bacteria in a patient with recurrent localized gingival enlargement before and after gingivectomy treatment. A 26-year-old woman came to AG Dental Care Clinic, South Sulawesi, Indonesia, in October 2015 with a chief complaint that her gingiva often bled spontaneously and she felt pain on her gingiva and felt less comfortable and no self-confidence with her anterior and posterior gingival condition on the right maxilla region which is slightly larger than normal. She often felt that her gingiva could bleed spontaneously when she was talking or remains silent though. The patient is disturbed by the malodor she felt. At that moment, the patient sought for gingivectomy treatment. Three years afterward, the patient came back with the same complaint. Gingival crevicular fluid has been taken from the gingival sulcus before and after gingivectomy. Clinical and GCF follow-up examination was performed one week and three weeks after gingivectomy, and successful results on biological, functional, and aesthetic parameters were observed.
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institution Kabale University
issn 2090-6447
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language English
publishDate 2018-01-01
publisher Wiley
record_format Article
series Case Reports in Dentistry
spelling doaj-art-8f6e1ea82f41416dba352e3c1e3dee182025-02-03T06:46:23ZengWileyCase Reports in Dentistry2090-64472090-64552018-01-01201810.1155/2018/36705833670583Change of TGF-β1 Gene Expression and TGF-β1 Protein Level in Gingival Crevicular Fluid and Identification of Plaque Bacteria in a Patient with Recurrent Localized Gingival Enlargement before and after GingivectomyLilies Anggarwati Astuti0Mochammad Hatta1Sri Oktawati2Rosdiana Natzir3Ressy Dwiyanti4Post-Graduate Program of Medical Sciences, Faculty of Medicine, University of Hasanuddin, Makassar, IndonesiaMolecular Biology and Immunology Laboratory, Faculty of Medicine, University of Hasanuddin, Makassar, IndonesiaDepartment of Periodontology, Faculty of Dentistry, University of Hasanuddin, Makassar, IndonesiaDepartment of Biochemistry, Faculty of Medicine, University of Hasanuddin, Makassar, IndonesiaPost-Graduate Program of Medical Sciences, Faculty of Medicine, University of Hasanuddin, Makassar, IndonesiaThis case report highlights the change of TGF-β1 gene expressions and TGF-β1 protein level in gingival crevicular fluid (GCF) and identification of plaque bacteria in a patient with recurrent localized gingival enlargement before and after gingivectomy treatment. A 26-year-old woman came to AG Dental Care Clinic, South Sulawesi, Indonesia, in October 2015 with a chief complaint that her gingiva often bled spontaneously and she felt pain on her gingiva and felt less comfortable and no self-confidence with her anterior and posterior gingival condition on the right maxilla region which is slightly larger than normal. She often felt that her gingiva could bleed spontaneously when she was talking or remains silent though. The patient is disturbed by the malodor she felt. At that moment, the patient sought for gingivectomy treatment. Three years afterward, the patient came back with the same complaint. Gingival crevicular fluid has been taken from the gingival sulcus before and after gingivectomy. Clinical and GCF follow-up examination was performed one week and three weeks after gingivectomy, and successful results on biological, functional, and aesthetic parameters were observed.http://dx.doi.org/10.1155/2018/3670583
spellingShingle Lilies Anggarwati Astuti
Mochammad Hatta
Sri Oktawati
Rosdiana Natzir
Ressy Dwiyanti
Change of TGF-β1 Gene Expression and TGF-β1 Protein Level in Gingival Crevicular Fluid and Identification of Plaque Bacteria in a Patient with Recurrent Localized Gingival Enlargement before and after Gingivectomy
Case Reports in Dentistry
title Change of TGF-β1 Gene Expression and TGF-β1 Protein Level in Gingival Crevicular Fluid and Identification of Plaque Bacteria in a Patient with Recurrent Localized Gingival Enlargement before and after Gingivectomy
title_full Change of TGF-β1 Gene Expression and TGF-β1 Protein Level in Gingival Crevicular Fluid and Identification of Plaque Bacteria in a Patient with Recurrent Localized Gingival Enlargement before and after Gingivectomy
title_fullStr Change of TGF-β1 Gene Expression and TGF-β1 Protein Level in Gingival Crevicular Fluid and Identification of Plaque Bacteria in a Patient with Recurrent Localized Gingival Enlargement before and after Gingivectomy
title_full_unstemmed Change of TGF-β1 Gene Expression and TGF-β1 Protein Level in Gingival Crevicular Fluid and Identification of Plaque Bacteria in a Patient with Recurrent Localized Gingival Enlargement before and after Gingivectomy
title_short Change of TGF-β1 Gene Expression and TGF-β1 Protein Level in Gingival Crevicular Fluid and Identification of Plaque Bacteria in a Patient with Recurrent Localized Gingival Enlargement before and after Gingivectomy
title_sort change of tgf β1 gene expression and tgf β1 protein level in gingival crevicular fluid and identification of plaque bacteria in a patient with recurrent localized gingival enlargement before and after gingivectomy
url http://dx.doi.org/10.1155/2018/3670583
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