R5S4TRAIL ameliorates radiation-induced pulmonary fibrosis by alleviating inflammatory responses and promoting apoptosis of fibroblasts

R5S4TRAIL ameliorates radiation-induced pulmonary fibrosis by alleviating inflammatory responses and promoting apoptosis of fibroblasts

BackgroundRadiation-induced pulmonary fibrosis (RIPF) is a chronic, fatal and irreversible disease that develops after a consequence of thoracic radiation therapy and few effective treatments have been developed for this condition. Repeated inflammation and excessive accumulation of fibroblasts are...

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Bibliographic Details
Main Authors: Yaqin Zhao, Yuanfeng Wei, Wanting Hou, Xianzhou Huang, Qiaoqi Li, Cheng Yi
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Immunology
Subjects:
R5S4TRAIL
radiation-induced pulmonary fibrosis (RIPF)
inflammatory
apoptosis
death receptor (DR)
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1600776/full
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