Nocardiosis in a Kidney-Pancreas Transplant
34-year-old man with chronic renal and pancreas failure in complicated diabetic disease received a kidney-pancreas transplantation. On the 32nd postoperative day, an acute kidney rejection occurred and resolved with OKT3 therapy. The patient also presented refractory urinary infection by E. Fecalis...
Saved in:
Main Authors: | , , , , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2010-01-01
|
Series: | Journal of Transplantation |
Online Access: | http://dx.doi.org/10.1155/2010/573234 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
_version_ | 1832558116314546176 |
---|---|
author | I. Fontana G. Gasloli A. Magoni Rossi C. Bornacina F. Dodi M. Bertocchi O. Soro P. Diviacco A. De Negri E. Bocci C. Ferrari A. Giannone Umberto Valente |
author_facet | I. Fontana G. Gasloli A. Magoni Rossi C. Bornacina F. Dodi M. Bertocchi O. Soro P. Diviacco A. De Negri E. Bocci C. Ferrari A. Giannone Umberto Valente |
author_sort | I. Fontana |
collection | DOAJ |
description | 34-year-old man with chronic renal and pancreas failure in complicated diabetic disease received a kidney-pancreas transplantation. On the 32nd postoperative day, an acute kidney rejection occurred and resolved with OKT3 therapy. The patient also presented refractory urinary infection by E. Fecalis and M. Morganii, and a focal bronchopneumonia in the right-basal lobe resolved with elective chemotherapy. During the 50th post-operative day, an intense soft tissue inflammation localized in the first left metatarsal-phalangeal articulation occurred (Figure 1) followed by an abscess with a cutaneous fistula and extension to the almost totality of foot area. The radiological exam revealed a small osteo-lacunar image localized in the proximal phalanx head of the first finger foot. From the cultural examination of the purulent material, N. Asteroides was identified. An amoxicillin-based treatment was started and continued for three months, with the complete resolution of infection This case is reported for its rarity in our casuistry, and for its difficult differential diagnosis with other potentially serious infections. |
format | Article |
id | doaj-art-8f460fbd9a9e4393b86060568399a51b |
institution | Kabale University |
issn | 2090-0007 2090-0015 |
language | English |
publishDate | 2010-01-01 |
publisher | Wiley |
record_format | Article |
series | Journal of Transplantation |
spelling | doaj-art-8f460fbd9a9e4393b86060568399a51b2025-02-03T01:33:18ZengWileyJournal of Transplantation2090-00072090-00152010-01-01201010.1155/2010/573234573234Nocardiosis in a Kidney-Pancreas TransplantI. Fontana0G. Gasloli1A. Magoni Rossi2C. Bornacina3F. Dodi4M. Bertocchi5O. Soro6P. Diviacco7A. De Negri8E. Bocci9C. Ferrari10A. Giannone11Umberto Valente12Department of Transplantation, San Martino University Hospital, L.go R. Benzi 10, 16132 Genoa, ItalyDepartment of Transplantation, San Martino University Hospital, L.go R. Benzi 10, 16132 Genoa, ItalyDepartment of Transplantation, San Martino University Hospital, L.go R. Benzi 10, 16132 Genoa, ItalyDepartment of Dermatology, University of Western Pindemont, via Solaroli 17, 28100 Novara, ItalyDepartment of Transplantation, San Martino University Hospital, L.go R. Benzi 10, 16132 Genoa, ItalyDepartment of Transplantation, San Martino University Hospital, L.go R. Benzi 10, 16132 Genoa, ItalyDepartment of Transplantation, San Martino University Hospital, L.go R. Benzi 10, 16132 Genoa, ItalyDepartment of Transplantation, San Martino University Hospital, L.go R. Benzi 10, 16132 Genoa, ItalyDepartment of Transplantation, San Martino University Hospital, L.go R. Benzi 10, 16132 Genoa, ItalyDepartment of Transplantation, San Martino University Hospital, L.go R. Benzi 10, 16132 Genoa, ItalyDepartment of Transplantation, San Martino University Hospital, L.go R. Benzi 10, 16132 Genoa, ItalyDepartment of Transplantation, San Martino University Hospital, L.go R. Benzi 10, 16132 Genoa, ItalyDepartment of Transplantation, San Martino University Hospital, L.go R. Benzi 10, 16132 Genoa, Italy34-year-old man with chronic renal and pancreas failure in complicated diabetic disease received a kidney-pancreas transplantation. On the 32nd postoperative day, an acute kidney rejection occurred and resolved with OKT3 therapy. The patient also presented refractory urinary infection by E. Fecalis and M. Morganii, and a focal bronchopneumonia in the right-basal lobe resolved with elective chemotherapy. During the 50th post-operative day, an intense soft tissue inflammation localized in the first left metatarsal-phalangeal articulation occurred (Figure 1) followed by an abscess with a cutaneous fistula and extension to the almost totality of foot area. The radiological exam revealed a small osteo-lacunar image localized in the proximal phalanx head of the first finger foot. From the cultural examination of the purulent material, N. Asteroides was identified. An amoxicillin-based treatment was started and continued for three months, with the complete resolution of infection This case is reported for its rarity in our casuistry, and for its difficult differential diagnosis with other potentially serious infections.http://dx.doi.org/10.1155/2010/573234 |
spellingShingle | I. Fontana G. Gasloli A. Magoni Rossi C. Bornacina F. Dodi M. Bertocchi O. Soro P. Diviacco A. De Negri E. Bocci C. Ferrari A. Giannone Umberto Valente Nocardiosis in a Kidney-Pancreas Transplant Journal of Transplantation |
title | Nocardiosis in a Kidney-Pancreas Transplant |
title_full | Nocardiosis in a Kidney-Pancreas Transplant |
title_fullStr | Nocardiosis in a Kidney-Pancreas Transplant |
title_full_unstemmed | Nocardiosis in a Kidney-Pancreas Transplant |
title_short | Nocardiosis in a Kidney-Pancreas Transplant |
title_sort | nocardiosis in a kidney pancreas transplant |
url | http://dx.doi.org/10.1155/2010/573234 |
work_keys_str_mv | AT ifontana nocardiosisinakidneypancreastransplant AT ggasloli nocardiosisinakidneypancreastransplant AT amagonirossi nocardiosisinakidneypancreastransplant AT cbornacina nocardiosisinakidneypancreastransplant AT fdodi nocardiosisinakidneypancreastransplant AT mbertocchi nocardiosisinakidneypancreastransplant AT osoro nocardiosisinakidneypancreastransplant AT pdiviacco nocardiosisinakidneypancreastransplant AT adenegri nocardiosisinakidneypancreastransplant AT ebocci nocardiosisinakidneypancreastransplant AT cferrari nocardiosisinakidneypancreastransplant AT agiannone nocardiosisinakidneypancreastransplant AT umbertovalente nocardiosisinakidneypancreastransplant |