The relationship between Helicobacter pylori and pityriasis versicolor
Background Although the immune dysregulation caused by Helicobacter pylori has been linked to the pathogenesis of many dermatological diseases, the link between H. pylori infection and pityriasis versicolor (PVC) has not been largely verified. Objective To study the probable association between acti...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2025-01-01
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| Series: | Journal of the Egyptian Women’s Dermatologic Society |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/jewd.jewd_34_24 |
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| author | May H. El Samahy Raafat Z. Abdelrahman Hossam O. Ibrahim Azza E. Mostafa |
| author_facet | May H. El Samahy Raafat Z. Abdelrahman Hossam O. Ibrahim Azza E. Mostafa |
| author_sort | May H. El Samahy |
| collection | DOAJ |
| description | Background
Although the immune dysregulation caused by Helicobacter pylori has been linked to the pathogenesis of many dermatological diseases, the link between H. pylori infection and pityriasis versicolor (PVC) has not been largely verified.
Objective
To study the probable association between active H. pylori infection and PVC prevalence and clinical parameters.
Patients and methods
The present case control study included 65 male patients with PVC (group A) and 65 dermatologically free patients (group B). Active H. pylori infection was detected in both groups using H. pylori stool antigen test (SAT). In group A, patients who tested SAT positive were subjected to measurement of anti-H. pylori immunoglobulin (Ig)G and IgA and interleukin (IL)-10 serum levels.
Results
The frequency of H. pylori was equal (61.5%) in both study groups. The various clinical parameters of PVC did not significantly differ between SAT-positive and SAT-negative patients. In group A, H. pylori-infected patients had elevated IgG and IgA serum titer, while IL-10 level was in most cases (65%) low. No significant relation was detected between the H. pylori serological markers and the PVC clinical parameters.
Conclusion
Active H. pylori infection did not impact the prevalence or clinical features of PVC. Elevated H. pylori IgG and IgA levels did not vary differentially in relation to PVC clinical features. Moreover, serum IL-10 level in active H. pylori-infected patients with PVC was not elevated. Accordingly, its role as a systemic immunosuppressive cytokine predisposing for PVC was unverified in this study. |
| format | Article |
| id | doaj-art-8f3ed7f637564fe69df90f058d7a9478 |
| institution | Kabale University |
| issn | 2090-2565 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of the Egyptian Women’s Dermatologic Society |
| spelling | doaj-art-8f3ed7f637564fe69df90f058d7a94782025-01-20T04:38:49ZengWolters Kluwer Medknow PublicationsJournal of the Egyptian Women’s Dermatologic Society2090-25652025-01-01221626910.4103/jewd.jewd_34_24The relationship between Helicobacter pylori and pityriasis versicolorMay H. El SamahyRaafat Z. AbdelrahmanHossam O. IbrahimAzza E. MostafaBackground Although the immune dysregulation caused by Helicobacter pylori has been linked to the pathogenesis of many dermatological diseases, the link between H. pylori infection and pityriasis versicolor (PVC) has not been largely verified. Objective To study the probable association between active H. pylori infection and PVC prevalence and clinical parameters. Patients and methods The present case control study included 65 male patients with PVC (group A) and 65 dermatologically free patients (group B). Active H. pylori infection was detected in both groups using H. pylori stool antigen test (SAT). In group A, patients who tested SAT positive were subjected to measurement of anti-H. pylori immunoglobulin (Ig)G and IgA and interleukin (IL)-10 serum levels. Results The frequency of H. pylori was equal (61.5%) in both study groups. The various clinical parameters of PVC did not significantly differ between SAT-positive and SAT-negative patients. In group A, H. pylori-infected patients had elevated IgG and IgA serum titer, while IL-10 level was in most cases (65%) low. No significant relation was detected between the H. pylori serological markers and the PVC clinical parameters. Conclusion Active H. pylori infection did not impact the prevalence or clinical features of PVC. Elevated H. pylori IgG and IgA levels did not vary differentially in relation to PVC clinical features. Moreover, serum IL-10 level in active H. pylori-infected patients with PVC was not elevated. Accordingly, its role as a systemic immunosuppressive cytokine predisposing for PVC was unverified in this study.https://journals.lww.com/10.4103/jewd.jewd_34_24helicobacter pyloriinterleukin-10pityriasis versicolor |
| spellingShingle | May H. El Samahy Raafat Z. Abdelrahman Hossam O. Ibrahim Azza E. Mostafa The relationship between Helicobacter pylori and pityriasis versicolor Journal of the Egyptian Women’s Dermatologic Society helicobacter pylori interleukin-10 pityriasis versicolor |
| title | The relationship between Helicobacter pylori and pityriasis versicolor |
| title_full | The relationship between Helicobacter pylori and pityriasis versicolor |
| title_fullStr | The relationship between Helicobacter pylori and pityriasis versicolor |
| title_full_unstemmed | The relationship between Helicobacter pylori and pityriasis versicolor |
| title_short | The relationship between Helicobacter pylori and pityriasis versicolor |
| title_sort | relationship between helicobacter pylori and pityriasis versicolor |
| topic | helicobacter pylori interleukin-10 pityriasis versicolor |
| url | https://journals.lww.com/10.4103/jewd.jewd_34_24 |
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