Benzoylaconine: Potential Therapeutic Agent for Cardiovascular Diseases From Fuzi

Modern pharmacological studies have elucidated the presence of aconitine (AC) alkaloids, polysaccharides, and saponins as the primary bioactive constituents of Fuzi. Among these, benzoylaconine, a pivotal active compound, demonstrates notable pharmacological properties including antitumor, anti-infl...

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Main Authors: Chenggang Xu, Le Tang, Lixin Hu, Yunzhe Huang, Jin Tang, Xiaohu Wang, Feng Wang
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Cardiovascular Therapeutics
Online Access:http://dx.doi.org/10.1155/2024/4878103
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author Chenggang Xu
Le Tang
Lixin Hu
Yunzhe Huang
Jin Tang
Xiaohu Wang
Feng Wang
author_facet Chenggang Xu
Le Tang
Lixin Hu
Yunzhe Huang
Jin Tang
Xiaohu Wang
Feng Wang
author_sort Chenggang Xu
collection DOAJ
description Modern pharmacological studies have elucidated the presence of aconitine (AC) alkaloids, polysaccharides, and saponins as the primary bioactive constituents of Fuzi. Among these, benzoylaconine, a pivotal active compound, demonstrates notable pharmacological properties including antitumor, anti-inflammatory, and cardiovascular protective effects. In recent years, benzoylaconine has garnered significant attention in basic research on heart diseases, emerging as a focal point of investigation. This paper presents a comprehensive review of the pharmacological effects of benzoylaconine, alongside an overview of advancements in metabolic characterization. The objective is to furnish valuable insights that can serve as a cornerstone for further exploration, utilization, and advancement of benzoylaconine in pharmacological research.
format Article
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institution Kabale University
issn 1755-5922
language English
publishDate 2024-01-01
publisher Wiley
record_format Article
series Cardiovascular Therapeutics
spelling doaj-art-8f3453b729e445359c25968963cee6f52025-02-03T07:23:45ZengWileyCardiovascular Therapeutics1755-59222024-01-01202410.1155/2024/4878103Benzoylaconine: Potential Therapeutic Agent for Cardiovascular Diseases From FuziChenggang Xu0Le Tang1Lixin Hu2Yunzhe Huang3Jin Tang4Xiaohu Wang5Feng Wang6Department of CardiologyPharmacology CollegeDepartment of PharmaceuticsGraduate SchoolGraduate SchoolDepartment of PharmaceuticsDepartment of CardiologyModern pharmacological studies have elucidated the presence of aconitine (AC) alkaloids, polysaccharides, and saponins as the primary bioactive constituents of Fuzi. Among these, benzoylaconine, a pivotal active compound, demonstrates notable pharmacological properties including antitumor, anti-inflammatory, and cardiovascular protective effects. In recent years, benzoylaconine has garnered significant attention in basic research on heart diseases, emerging as a focal point of investigation. This paper presents a comprehensive review of the pharmacological effects of benzoylaconine, alongside an overview of advancements in metabolic characterization. The objective is to furnish valuable insights that can serve as a cornerstone for further exploration, utilization, and advancement of benzoylaconine in pharmacological research.http://dx.doi.org/10.1155/2024/4878103
spellingShingle Chenggang Xu
Le Tang
Lixin Hu
Yunzhe Huang
Jin Tang
Xiaohu Wang
Feng Wang
Benzoylaconine: Potential Therapeutic Agent for Cardiovascular Diseases From Fuzi
Cardiovascular Therapeutics
title Benzoylaconine: Potential Therapeutic Agent for Cardiovascular Diseases From Fuzi
title_full Benzoylaconine: Potential Therapeutic Agent for Cardiovascular Diseases From Fuzi
title_fullStr Benzoylaconine: Potential Therapeutic Agent for Cardiovascular Diseases From Fuzi
title_full_unstemmed Benzoylaconine: Potential Therapeutic Agent for Cardiovascular Diseases From Fuzi
title_short Benzoylaconine: Potential Therapeutic Agent for Cardiovascular Diseases From Fuzi
title_sort benzoylaconine potential therapeutic agent for cardiovascular diseases from fuzi
url http://dx.doi.org/10.1155/2024/4878103
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