Benzoylaconine: Potential Therapeutic Agent for Cardiovascular Diseases From Fuzi

Modern pharmacological studies have elucidated the presence of aconitine (AC) alkaloids, polysaccharides, and saponins as the primary bioactive constituents of Fuzi. Among these, benzoylaconine, a pivotal active compound, demonstrates notable pharmacological properties including antitumor, anti-infl...

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Bibliographic Details
Main Authors: Chenggang Xu, Le Tang, Lixin Hu, Yunzhe Huang, Jin Tang, Xiaohu Wang, Feng Wang
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Cardiovascular Therapeutics
Online Access:http://dx.doi.org/10.1155/2024/4878103
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Summary:Modern pharmacological studies have elucidated the presence of aconitine (AC) alkaloids, polysaccharides, and saponins as the primary bioactive constituents of Fuzi. Among these, benzoylaconine, a pivotal active compound, demonstrates notable pharmacological properties including antitumor, anti-inflammatory, and cardiovascular protective effects. In recent years, benzoylaconine has garnered significant attention in basic research on heart diseases, emerging as a focal point of investigation. This paper presents a comprehensive review of the pharmacological effects of benzoylaconine, alongside an overview of advancements in metabolic characterization. The objective is to furnish valuable insights that can serve as a cornerstone for further exploration, utilization, and advancement of benzoylaconine in pharmacological research.
ISSN:1755-5922