Multiple Thromboses in a Patient with Systemic Lupus Erythematosus after Splenectomy

Antiphospholipid syndrome is a disorder presenting with arterial or venous thrombus and a history of fetal loss. Early diagnosis and adequate treatment is important to prevent multiple organ failures. Here, we described a woman with a two-year history of systemic lupus erythematosus with severe neph...

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Main Author: Deng-Ho Yang
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Case Reports in Immunology
Online Access:http://dx.doi.org/10.1155/2012/813629
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author Deng-Ho Yang
author_facet Deng-Ho Yang
author_sort Deng-Ho Yang
collection DOAJ
description Antiphospholipid syndrome is a disorder presenting with arterial or venous thrombus and a history of fetal loss. Early diagnosis and adequate treatment is important to prevent multiple organ failures. Here, we described a woman with a two-year history of systemic lupus erythematosus with severe nephrotic syndrome, manifested multiple thrombi over the portal vein and the inferior vena cava, combined with acute renal infarction. The patient underwent splenectomy 10 months ago. Initially, she received anticoagulant treatment and low-dose glucocorticoid, but multiple organ failure progressed. After emergency plasma exchange followed by glucocorticoid pulse therapy, the patient recovered.
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spelling doaj-art-8f337c8a9c404e2bb41e607d9a39834c2025-02-03T01:32:33ZengWileyCase Reports in Immunology2090-66092090-66172012-01-01201210.1155/2012/813629813629Multiple Thromboses in a Patient with Systemic Lupus Erythematosus after SplenectomyDeng-Ho Yang0Division of Rheumatology/Immunology/Allergy, Department of Internal Medicine, Armed-Forces Taichung General Hospital, Number 348, Section 2, Chung Shan Road, Taiping District, Taichung City 411, TaiwanAntiphospholipid syndrome is a disorder presenting with arterial or venous thrombus and a history of fetal loss. Early diagnosis and adequate treatment is important to prevent multiple organ failures. Here, we described a woman with a two-year history of systemic lupus erythematosus with severe nephrotic syndrome, manifested multiple thrombi over the portal vein and the inferior vena cava, combined with acute renal infarction. The patient underwent splenectomy 10 months ago. Initially, she received anticoagulant treatment and low-dose glucocorticoid, but multiple organ failure progressed. After emergency plasma exchange followed by glucocorticoid pulse therapy, the patient recovered.http://dx.doi.org/10.1155/2012/813629
spellingShingle Deng-Ho Yang
Multiple Thromboses in a Patient with Systemic Lupus Erythematosus after Splenectomy
Case Reports in Immunology
title Multiple Thromboses in a Patient with Systemic Lupus Erythematosus after Splenectomy
title_full Multiple Thromboses in a Patient with Systemic Lupus Erythematosus after Splenectomy
title_fullStr Multiple Thromboses in a Patient with Systemic Lupus Erythematosus after Splenectomy
title_full_unstemmed Multiple Thromboses in a Patient with Systemic Lupus Erythematosus after Splenectomy
title_short Multiple Thromboses in a Patient with Systemic Lupus Erythematosus after Splenectomy
title_sort multiple thromboses in a patient with systemic lupus erythematosus after splenectomy
url http://dx.doi.org/10.1155/2012/813629
work_keys_str_mv AT denghoyang multiplethrombosesinapatientwithsystemiclupuserythematosusaftersplenectomy