Sarcomatoid (Spindle Cell) Carcinoma of Tongue: A Report of Two Cases

Sarcomatoid Carcinoma (SC) is an unusual and aggressive variant of squamous cell carcinoma, which frequently recurs and metastasizes; for this reason, the right diagnosis is very important. It is considered to be a biphasic tumor made up of cells from squamous and spindle cells carcinoma with a sarc...

Full description

Saved in:
Bibliographic Details
Main Authors: Montserrat Reyes, Gina Pennacchiotti, Fabio Valdes, Rodrigo Montes, Marcelo Veloso, Maria Angélica Matamala, Luis Zanolli, Gonzalo Rojas-Alcayaga
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Case Reports in Dentistry
Online Access:http://dx.doi.org/10.1155/2015/780856
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832555548565831680
author Montserrat Reyes
Gina Pennacchiotti
Fabio Valdes
Rodrigo Montes
Marcelo Veloso
Maria Angélica Matamala
Luis Zanolli
Gonzalo Rojas-Alcayaga
author_facet Montserrat Reyes
Gina Pennacchiotti
Fabio Valdes
Rodrigo Montes
Marcelo Veloso
Maria Angélica Matamala
Luis Zanolli
Gonzalo Rojas-Alcayaga
author_sort Montserrat Reyes
collection DOAJ
description Sarcomatoid Carcinoma (SC) is an unusual and aggressive variant of squamous cell carcinoma, which frequently recurs and metastasizes; for this reason, the right diagnosis is very important. It is considered to be a biphasic tumor made up of cells from squamous and spindle cells carcinoma with a sarcomatous aspect, but of epithelial origin. The diagnosis often represents a clinical-pathological challenge where the study with immunohistochemical technique (IHC) is key to the histopathological diagnosis. The reported cases related to oral mucosa are limited. In this work we present two SC cases where the use of IHC allowed us to achieve a conclusive diagnosis.
format Article
id doaj-art-8f2febf81955462ca5aa0212c8c234c2
institution Kabale University
issn 2090-6447
2090-6455
language English
publishDate 2015-01-01
publisher Wiley
record_format Article
series Case Reports in Dentistry
spelling doaj-art-8f2febf81955462ca5aa0212c8c234c22025-02-03T05:48:01ZengWileyCase Reports in Dentistry2090-64472090-64552015-01-01201510.1155/2015/780856780856Sarcomatoid (Spindle Cell) Carcinoma of Tongue: A Report of Two CasesMontserrat Reyes0Gina Pennacchiotti1Fabio Valdes2Rodrigo Montes3Marcelo Veloso4Maria Angélica Matamala5Luis Zanolli6Gonzalo Rojas-Alcayaga7Department of Pathology and Oral Medicine, Faculty of Dentistry, University of Chile, Sergio Livingstone Pohlhammer 943, Independencia, 8380492 Santiago, ChileDepartment of Pathology and Oral Medicine, Faculty of Dentistry, University of Chile, Sergio Livingstone Pohlhammer 943, Independencia, 8380492 Santiago, ChileNational Cancer Institute, Profesor Zañartu 1010, Independencia, 8380492 Santiago, ChileNational Cancer Institute, Profesor Zañartu 1010, Independencia, 8380492 Santiago, ChileNational Cancer Institute, Profesor Zañartu 1010, Independencia, 8380492 Santiago, ChileNational Cancer Institute, Profesor Zañartu 1010, Independencia, 8380492 Santiago, ChileNational Cancer Institute, Profesor Zañartu 1010, Independencia, 8380492 Santiago, ChileDepartment of Pathology and Oral Medicine, Faculty of Dentistry, University of Chile, Sergio Livingstone Pohlhammer 943, Independencia, 8380492 Santiago, ChileSarcomatoid Carcinoma (SC) is an unusual and aggressive variant of squamous cell carcinoma, which frequently recurs and metastasizes; for this reason, the right diagnosis is very important. It is considered to be a biphasic tumor made up of cells from squamous and spindle cells carcinoma with a sarcomatous aspect, but of epithelial origin. The diagnosis often represents a clinical-pathological challenge where the study with immunohistochemical technique (IHC) is key to the histopathological diagnosis. The reported cases related to oral mucosa are limited. In this work we present two SC cases where the use of IHC allowed us to achieve a conclusive diagnosis.http://dx.doi.org/10.1155/2015/780856
spellingShingle Montserrat Reyes
Gina Pennacchiotti
Fabio Valdes
Rodrigo Montes
Marcelo Veloso
Maria Angélica Matamala
Luis Zanolli
Gonzalo Rojas-Alcayaga
Sarcomatoid (Spindle Cell) Carcinoma of Tongue: A Report of Two Cases
Case Reports in Dentistry
title Sarcomatoid (Spindle Cell) Carcinoma of Tongue: A Report of Two Cases
title_full Sarcomatoid (Spindle Cell) Carcinoma of Tongue: A Report of Two Cases
title_fullStr Sarcomatoid (Spindle Cell) Carcinoma of Tongue: A Report of Two Cases
title_full_unstemmed Sarcomatoid (Spindle Cell) Carcinoma of Tongue: A Report of Two Cases
title_short Sarcomatoid (Spindle Cell) Carcinoma of Tongue: A Report of Two Cases
title_sort sarcomatoid spindle cell carcinoma of tongue a report of two cases
url http://dx.doi.org/10.1155/2015/780856
work_keys_str_mv AT montserratreyes sarcomatoidspindlecellcarcinomaoftongueareportoftwocases
AT ginapennacchiotti sarcomatoidspindlecellcarcinomaoftongueareportoftwocases
AT fabiovaldes sarcomatoidspindlecellcarcinomaoftongueareportoftwocases
AT rodrigomontes sarcomatoidspindlecellcarcinomaoftongueareportoftwocases
AT marceloveloso sarcomatoidspindlecellcarcinomaoftongueareportoftwocases
AT mariaangelicamatamala sarcomatoidspindlecellcarcinomaoftongueareportoftwocases
AT luiszanolli sarcomatoidspindlecellcarcinomaoftongueareportoftwocases
AT gonzalorojasalcayaga sarcomatoidspindlecellcarcinomaoftongueareportoftwocases