Sarcomatoid (Spindle Cell) Carcinoma of Tongue: A Report of Two Cases
Sarcomatoid Carcinoma (SC) is an unusual and aggressive variant of squamous cell carcinoma, which frequently recurs and metastasizes; for this reason, the right diagnosis is very important. It is considered to be a biphasic tumor made up of cells from squamous and spindle cells carcinoma with a sarc...
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Format: | Article |
Language: | English |
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Wiley
2015-01-01
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Series: | Case Reports in Dentistry |
Online Access: | http://dx.doi.org/10.1155/2015/780856 |
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author | Montserrat Reyes Gina Pennacchiotti Fabio Valdes Rodrigo Montes Marcelo Veloso Maria Angélica Matamala Luis Zanolli Gonzalo Rojas-Alcayaga |
author_facet | Montserrat Reyes Gina Pennacchiotti Fabio Valdes Rodrigo Montes Marcelo Veloso Maria Angélica Matamala Luis Zanolli Gonzalo Rojas-Alcayaga |
author_sort | Montserrat Reyes |
collection | DOAJ |
description | Sarcomatoid Carcinoma (SC) is an unusual and aggressive variant of squamous cell carcinoma, which frequently recurs and metastasizes; for this reason, the right diagnosis is very important. It is considered to be a biphasic tumor made up of cells from squamous and spindle cells carcinoma with a sarcomatous aspect, but of epithelial origin. The diagnosis often represents a clinical-pathological challenge where the study with immunohistochemical technique (IHC) is key to the histopathological diagnosis. The reported cases related to oral mucosa are limited. In this work we present two SC cases where the use of IHC allowed us to achieve a conclusive diagnosis. |
format | Article |
id | doaj-art-8f2febf81955462ca5aa0212c8c234c2 |
institution | Kabale University |
issn | 2090-6447 2090-6455 |
language | English |
publishDate | 2015-01-01 |
publisher | Wiley |
record_format | Article |
series | Case Reports in Dentistry |
spelling | doaj-art-8f2febf81955462ca5aa0212c8c234c22025-02-03T05:48:01ZengWileyCase Reports in Dentistry2090-64472090-64552015-01-01201510.1155/2015/780856780856Sarcomatoid (Spindle Cell) Carcinoma of Tongue: A Report of Two CasesMontserrat Reyes0Gina Pennacchiotti1Fabio Valdes2Rodrigo Montes3Marcelo Veloso4Maria Angélica Matamala5Luis Zanolli6Gonzalo Rojas-Alcayaga7Department of Pathology and Oral Medicine, Faculty of Dentistry, University of Chile, Sergio Livingstone Pohlhammer 943, Independencia, 8380492 Santiago, ChileDepartment of Pathology and Oral Medicine, Faculty of Dentistry, University of Chile, Sergio Livingstone Pohlhammer 943, Independencia, 8380492 Santiago, ChileNational Cancer Institute, Profesor Zañartu 1010, Independencia, 8380492 Santiago, ChileNational Cancer Institute, Profesor Zañartu 1010, Independencia, 8380492 Santiago, ChileNational Cancer Institute, Profesor Zañartu 1010, Independencia, 8380492 Santiago, ChileNational Cancer Institute, Profesor Zañartu 1010, Independencia, 8380492 Santiago, ChileNational Cancer Institute, Profesor Zañartu 1010, Independencia, 8380492 Santiago, ChileDepartment of Pathology and Oral Medicine, Faculty of Dentistry, University of Chile, Sergio Livingstone Pohlhammer 943, Independencia, 8380492 Santiago, ChileSarcomatoid Carcinoma (SC) is an unusual and aggressive variant of squamous cell carcinoma, which frequently recurs and metastasizes; for this reason, the right diagnosis is very important. It is considered to be a biphasic tumor made up of cells from squamous and spindle cells carcinoma with a sarcomatous aspect, but of epithelial origin. The diagnosis often represents a clinical-pathological challenge where the study with immunohistochemical technique (IHC) is key to the histopathological diagnosis. The reported cases related to oral mucosa are limited. In this work we present two SC cases where the use of IHC allowed us to achieve a conclusive diagnosis.http://dx.doi.org/10.1155/2015/780856 |
spellingShingle | Montserrat Reyes Gina Pennacchiotti Fabio Valdes Rodrigo Montes Marcelo Veloso Maria Angélica Matamala Luis Zanolli Gonzalo Rojas-Alcayaga Sarcomatoid (Spindle Cell) Carcinoma of Tongue: A Report of Two Cases Case Reports in Dentistry |
title | Sarcomatoid (Spindle Cell) Carcinoma of Tongue: A Report of Two Cases |
title_full | Sarcomatoid (Spindle Cell) Carcinoma of Tongue: A Report of Two Cases |
title_fullStr | Sarcomatoid (Spindle Cell) Carcinoma of Tongue: A Report of Two Cases |
title_full_unstemmed | Sarcomatoid (Spindle Cell) Carcinoma of Tongue: A Report of Two Cases |
title_short | Sarcomatoid (Spindle Cell) Carcinoma of Tongue: A Report of Two Cases |
title_sort | sarcomatoid spindle cell carcinoma of tongue a report of two cases |
url | http://dx.doi.org/10.1155/2015/780856 |
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