Temperature-Responsive Gelation of Type I Collagen Solutions Involving Fibril Formation and Genipin Crosslinking as a Potential Injectable Hydrogel

We investigated the temperature-responsive gelation of collagen/genipin solutions using pepsin-solubilized collagen (PSC) and acid-solubilized collagen (ASC) as substrates. Gelation occurred in the PSC/genipin solutions at genipin concentrations 0–2 mM under moderate change in temperature from 25 to...

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Bibliographic Details
Main Authors: Shunji Yunoki, Yoshimi Ohyabu, Hirosuke Hatayama
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:International Journal of Biomaterials
Online Access:http://dx.doi.org/10.1155/2013/620765
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