Fatal Septic Shock in a Patient with Hemophagocytic Lymphohistiocytosis Associated with an Infectious Mononucleosis
The authors describe the case of a young woman who developed a clinical pictures resembling a septic shock-related multiple organ dysfunction syndrome a couple of months after having been diagnosed suffering from a hemophagocytic lymphohistiocytosis associated with an infectious mononucleosis. Despi...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Case Reports in Critical Care |
| Online Access: | http://dx.doi.org/10.1155/2018/9756050 |
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| author | Giorgio Berlot Ariella Tomasini Lorenzo Zandonà Eugenio Leonardo Rossana Bussani Nadia Zarrillo |
| author_facet | Giorgio Berlot Ariella Tomasini Lorenzo Zandonà Eugenio Leonardo Rossana Bussani Nadia Zarrillo |
| author_sort | Giorgio Berlot |
| collection | DOAJ |
| description | The authors describe the case of a young woman who developed a clinical pictures resembling a septic shock-related multiple organ dysfunction syndrome a couple of months after having been diagnosed suffering from a hemophagocytic lymphohistiocytosis associated with an infectious mononucleosis. Despite the aggressive treatment, which included antibiotics, vasopressors, IV immunoglobulins, and the use of an extracorporeal device aimed to remove mediators released both during sepsis and the cytokine storm determined by the hemophagocytic lymphohistiocytosis, the patient died. At the autopsy, an extremely uncommon aggressive lymphoma of Epstein-Barr virus-positive T-lymphocytes with systemic involvement was discovered. |
| format | Article |
| id | doaj-art-8f26a09f9bf44d27b29a8c2f6e22062a |
| institution | Kabale University |
| issn | 2090-6420 2090-6439 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Critical Care |
| spelling | doaj-art-8f26a09f9bf44d27b29a8c2f6e22062a2025-02-03T06:13:43ZengWileyCase Reports in Critical Care2090-64202090-64392018-01-01201810.1155/2018/97560509756050Fatal Septic Shock in a Patient with Hemophagocytic Lymphohistiocytosis Associated with an Infectious MononucleosisGiorgio Berlot0Ariella Tomasini1Lorenzo Zandonà2Eugenio Leonardo3Rossana Bussani4Nadia Zarrillo5University of Trieste, Department of Anesthesia and Intensive Care, Cattinara Hospital, 447, 34149, Trieste, ItalyUniversity of Trieste, Department of Anesthesia and Intensive Care, Cattinara Hospital, 447, 34149, Trieste, ItalyUniversity of Trieste, Department of Pathology, Cattinara Hospital, 447, 34149, Trieste, ItalyUniversity of Trieste, Department of Pathology, Cattinara Hospital, 447, 34149, Trieste, ItalyUniversity of Trieste, Department of Pathology, Cattinara Hospital, 447, 34149, Trieste, ItalyCaserta Hospital, Department of Anesthesia and Intensive Care, ItalyThe authors describe the case of a young woman who developed a clinical pictures resembling a septic shock-related multiple organ dysfunction syndrome a couple of months after having been diagnosed suffering from a hemophagocytic lymphohistiocytosis associated with an infectious mononucleosis. Despite the aggressive treatment, which included antibiotics, vasopressors, IV immunoglobulins, and the use of an extracorporeal device aimed to remove mediators released both during sepsis and the cytokine storm determined by the hemophagocytic lymphohistiocytosis, the patient died. At the autopsy, an extremely uncommon aggressive lymphoma of Epstein-Barr virus-positive T-lymphocytes with systemic involvement was discovered.http://dx.doi.org/10.1155/2018/9756050 |
| spellingShingle | Giorgio Berlot Ariella Tomasini Lorenzo Zandonà Eugenio Leonardo Rossana Bussani Nadia Zarrillo Fatal Septic Shock in a Patient with Hemophagocytic Lymphohistiocytosis Associated with an Infectious Mononucleosis Case Reports in Critical Care |
| title | Fatal Septic Shock in a Patient with Hemophagocytic Lymphohistiocytosis Associated with an Infectious Mononucleosis |
| title_full | Fatal Septic Shock in a Patient with Hemophagocytic Lymphohistiocytosis Associated with an Infectious Mononucleosis |
| title_fullStr | Fatal Septic Shock in a Patient with Hemophagocytic Lymphohistiocytosis Associated with an Infectious Mononucleosis |
| title_full_unstemmed | Fatal Septic Shock in a Patient with Hemophagocytic Lymphohistiocytosis Associated with an Infectious Mononucleosis |
| title_short | Fatal Septic Shock in a Patient with Hemophagocytic Lymphohistiocytosis Associated with an Infectious Mononucleosis |
| title_sort | fatal septic shock in a patient with hemophagocytic lymphohistiocytosis associated with an infectious mononucleosis |
| url | http://dx.doi.org/10.1155/2018/9756050 |
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