Exploring the anticandida potentials of nanoparticles fabricated from tea leaf (Camellia sinensis) extracts: a systematic review
Abstract Globally, large proportions of Candida species are becoming a major threat to human health as they are developing resistance to most available antifungal drugs. The recent adoption of nanoparticles as an intervening strategy against resistant microbes has proven efficient. Besides their ant...
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| Format: | Article |
| Language: | English |
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Springer
2025-01-01
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| Series: | Discover Materials |
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| Online Access: | https://doi.org/10.1007/s43939-025-00196-9 |
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| author | Naheem Adekilekun Tijani Abdullateef Opeyemi Afolabi Fred Mutanule Sujithkumar Ganesh Moorthy Danladi Makeri |
| author_facet | Naheem Adekilekun Tijani Abdullateef Opeyemi Afolabi Fred Mutanule Sujithkumar Ganesh Moorthy Danladi Makeri |
| author_sort | Naheem Adekilekun Tijani |
| collection | DOAJ |
| description | Abstract Globally, large proportions of Candida species are becoming a major threat to human health as they are developing resistance to most available antifungal drugs. The recent adoption of nanoparticles as an intervening strategy against resistant microbes has proven efficient. Besides their antifungal activities, several studies have reported the anticandida properties of nanoparticles fabricated from plant materials. In this systematic review, available data from the literature on the anticandida potentials of nanoparticles biosynthesized from tea leaf (Camellia sinensis) extracts were compiled and analyzed. A total of 30 studies were generated from a literature search in three electronic databases i.e. Scopus, PubMed, and Embase, in accordance to the PRISMA guidelines. The retrieved studies were filtered based on inclusion and exclusion criteria. We included nine (9) eligible articles that highlighted the antifungal efficacy of nanoparticles mediated from tea leaf extract against Candida species. From the selected articles, the antifungal effect of synthesized NPs against C. albicans, C. tropicalis, C. glabrata, C. dubliniensis, and C. parapsilosis was reported and expressed by the zone of inhibition (ZOI) diameter and the minimum inhibitory concentration (MIC). The studies analysis showed the potency of plant extract-mediated NPs against Candida species, regardless of the heterogeneity of results that was spotted in the diameter of ZOI presented from one study to another. |
| format | Article |
| id | doaj-art-8f13aaa110f54dd2bbcd241d0d431b89 |
| institution | Kabale University |
| issn | 2730-7727 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Springer |
| record_format | Article |
| series | Discover Materials |
| spelling | doaj-art-8f13aaa110f54dd2bbcd241d0d431b892025-01-26T12:57:36ZengSpringerDiscover Materials2730-77272025-01-015111010.1007/s43939-025-00196-9Exploring the anticandida potentials of nanoparticles fabricated from tea leaf (Camellia sinensis) extracts: a systematic reviewNaheem Adekilekun Tijani0Abdullateef Opeyemi Afolabi1Fred Mutanule2Sujithkumar Ganesh Moorthy3Danladi Makeri4Department of Microbiology and Immunology, Kampala International UniversityDepartment of Microbiology and Immunology, Kampala International UniversityDepartment of Microbiology and Immunology, Kampala International UniversityInstitut de Chimie Moléculaire de l’université de Bourgogne (ICMUB), UMR CNRS 6302, Université de BourgogneDepartment of Microbiology and Immunology, Kampala International UniversityAbstract Globally, large proportions of Candida species are becoming a major threat to human health as they are developing resistance to most available antifungal drugs. The recent adoption of nanoparticles as an intervening strategy against resistant microbes has proven efficient. Besides their antifungal activities, several studies have reported the anticandida properties of nanoparticles fabricated from plant materials. In this systematic review, available data from the literature on the anticandida potentials of nanoparticles biosynthesized from tea leaf (Camellia sinensis) extracts were compiled and analyzed. A total of 30 studies were generated from a literature search in three electronic databases i.e. Scopus, PubMed, and Embase, in accordance to the PRISMA guidelines. The retrieved studies were filtered based on inclusion and exclusion criteria. We included nine (9) eligible articles that highlighted the antifungal efficacy of nanoparticles mediated from tea leaf extract against Candida species. From the selected articles, the antifungal effect of synthesized NPs against C. albicans, C. tropicalis, C. glabrata, C. dubliniensis, and C. parapsilosis was reported and expressed by the zone of inhibition (ZOI) diameter and the minimum inhibitory concentration (MIC). The studies analysis showed the potency of plant extract-mediated NPs against Candida species, regardless of the heterogeneity of results that was spotted in the diameter of ZOI presented from one study to another.https://doi.org/10.1007/s43939-025-00196-9Camellia sinensisPhytoextractsNanoparticlesCandida infectionsAnticandida activity |
| spellingShingle | Naheem Adekilekun Tijani Abdullateef Opeyemi Afolabi Fred Mutanule Sujithkumar Ganesh Moorthy Danladi Makeri Exploring the anticandida potentials of nanoparticles fabricated from tea leaf (Camellia sinensis) extracts: a systematic review Discover Materials Camellia sinensis Phytoextracts Nanoparticles Candida infections Anticandida activity |
| title | Exploring the anticandida potentials of nanoparticles fabricated from tea leaf (Camellia sinensis) extracts: a systematic review |
| title_full | Exploring the anticandida potentials of nanoparticles fabricated from tea leaf (Camellia sinensis) extracts: a systematic review |
| title_fullStr | Exploring the anticandida potentials of nanoparticles fabricated from tea leaf (Camellia sinensis) extracts: a systematic review |
| title_full_unstemmed | Exploring the anticandida potentials of nanoparticles fabricated from tea leaf (Camellia sinensis) extracts: a systematic review |
| title_short | Exploring the anticandida potentials of nanoparticles fabricated from tea leaf (Camellia sinensis) extracts: a systematic review |
| title_sort | exploring the anticandida potentials of nanoparticles fabricated from tea leaf camellia sinensis extracts a systematic review |
| topic | Camellia sinensis Phytoextracts Nanoparticles Candida infections Anticandida activity |
| url | https://doi.org/10.1007/s43939-025-00196-9 |
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