Spontaneous Regression of Metastatic Papillary Thyroid Cancer in a Lymph Node
Spontaneous regression of cancer is defined as disappearance of cancer in the absence of specific therapy. In thyroid cancer patients with biochemically incomplete response to initial treatments, spontaneous decline in thyroglobulin levels without any cancer treatment is a well-known phenomenon; how...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Case Reports in Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2018/5873897 |
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| _version_ | 1832561718420570112 |
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| author | Jien Shim Jianyu Rao Run Yu |
| author_facet | Jien Shim Jianyu Rao Run Yu |
| author_sort | Jien Shim |
| collection | DOAJ |
| description | Spontaneous regression of cancer is defined as disappearance of cancer in the absence of specific therapy. In thyroid cancer patients with biochemically incomplete response to initial treatments, spontaneous decline in thyroglobulin levels without any cancer treatment is a well-known phenomenon; however, spontaneous regression of persistent or recurrent structural disease has not been reported. We here present a case of papillary thyroid cancer in a 58-year-old female who underwent total thyroidectomy and two radioiodine ablations. She had persistently elevated thyroglobulin levels. Six years after her initial treatments, she had biopsy-proven cervical lymph node metastasis. The patient opted not to undergo any further treatment. Over the course of the next 10 years, without any additional treatment, the lymph node disappeared and her thyroglobulin levels decreased to almost undetectable ranges, implying near-complete regression. Our case illustrates that metastatic papillary thyroid cancer in lymph nodes can regress spontaneously. |
| format | Article |
| id | doaj-art-8f043c96b571437ea9654d5412a3f705 |
| institution | Kabale University |
| issn | 2090-6501 2090-651X |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Endocrinology |
| spelling | doaj-art-8f043c96b571437ea9654d5412a3f7052025-02-03T01:24:27ZengWileyCase Reports in Endocrinology2090-65012090-651X2018-01-01201810.1155/2018/58738975873897Spontaneous Regression of Metastatic Papillary Thyroid Cancer in a Lymph NodeJien Shim0Jianyu Rao1Run Yu2Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, University of California, Los Angeles, David Geffen School of Medicine, Los Angeles, CA 90095, USADepartment of Pathology and Laboratory Medicine, University of California, Los Angeles, David Geffen School of Medicine, Los Angeles, CA 90095, USADivision of Endocrinology, Diabetes, and Metabolism, Department of Medicine, University of California, Los Angeles, David Geffen School of Medicine, Los Angeles, CA 90095, USASpontaneous regression of cancer is defined as disappearance of cancer in the absence of specific therapy. In thyroid cancer patients with biochemically incomplete response to initial treatments, spontaneous decline in thyroglobulin levels without any cancer treatment is a well-known phenomenon; however, spontaneous regression of persistent or recurrent structural disease has not been reported. We here present a case of papillary thyroid cancer in a 58-year-old female who underwent total thyroidectomy and two radioiodine ablations. She had persistently elevated thyroglobulin levels. Six years after her initial treatments, she had biopsy-proven cervical lymph node metastasis. The patient opted not to undergo any further treatment. Over the course of the next 10 years, without any additional treatment, the lymph node disappeared and her thyroglobulin levels decreased to almost undetectable ranges, implying near-complete regression. Our case illustrates that metastatic papillary thyroid cancer in lymph nodes can regress spontaneously.http://dx.doi.org/10.1155/2018/5873897 |
| spellingShingle | Jien Shim Jianyu Rao Run Yu Spontaneous Regression of Metastatic Papillary Thyroid Cancer in a Lymph Node Case Reports in Endocrinology |
| title | Spontaneous Regression of Metastatic Papillary Thyroid Cancer in a Lymph Node |
| title_full | Spontaneous Regression of Metastatic Papillary Thyroid Cancer in a Lymph Node |
| title_fullStr | Spontaneous Regression of Metastatic Papillary Thyroid Cancer in a Lymph Node |
| title_full_unstemmed | Spontaneous Regression of Metastatic Papillary Thyroid Cancer in a Lymph Node |
| title_short | Spontaneous Regression of Metastatic Papillary Thyroid Cancer in a Lymph Node |
| title_sort | spontaneous regression of metastatic papillary thyroid cancer in a lymph node |
| url | http://dx.doi.org/10.1155/2018/5873897 |
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