The Correlation between Microalbuminuria and Thyroid Nodules in Type 2 Diabetic Mellitus

Objective. To investigate the correlation between thyroid nodules and microalbuminuria in type 2 diabetic mellitus. Methods. A total of 270 patients with type 2 diabetes at Tongzhou Branch of Dongzhimen Hospital were enrolled in this retrospective study. Data were collected from the inpatient electr...

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Main Authors: Can Cao, Zhao-Li Cui, Juan Miao, Jing-Xin Zhou, Xiao-Nan Wang, Jian Jin
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:International Journal of Endocrinology
Online Access:http://dx.doi.org/10.1155/2022/2789279
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author Can Cao
Zhao-Li Cui
Juan Miao
Jing-Xin Zhou
Xiao-Nan Wang
Jian Jin
author_facet Can Cao
Zhao-Li Cui
Juan Miao
Jing-Xin Zhou
Xiao-Nan Wang
Jian Jin
author_sort Can Cao
collection DOAJ
description Objective. To investigate the correlation between thyroid nodules and microalbuminuria in type 2 diabetic mellitus. Methods. A total of 270 patients with type 2 diabetes at Tongzhou Branch of Dongzhimen Hospital were enrolled in this retrospective study. Data were collected from the inpatient electronic files between January 2018 and January 2020. The laboratory indexes of the two groups (thyroid nodule group with 172 cases and control group including 98 cases without thyroid nodules) were statistically analyzed by binomial logistic regression analysis and Spearman correlation analysis. Results. The proportion of microalbuminuria (MAU) in the thyroid nodule group was larger than that in the control group. Age, serum TT4, and FT4 in the thyroid nodule group were significantly higher compared with the control group. The binary logistic regression analysis indicated that age, sex, FT4, and MAU were the risk factors for thyroid nodule in T2DM patients. Spearman correlation analysis showed that the thyroid nodule was significantly positively correlated with MAU, age, FT4, and TT4. Conclusions. MAU might be an independent risk factor for thyroid nodule in type 2 diabetic mellitus.
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publisher Wiley
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series International Journal of Endocrinology
spelling doaj-art-8ed8cc3363db45a8b6f162ebc4ddd8b32025-02-03T01:10:58ZengWileyInternational Journal of Endocrinology1687-83452022-01-01202210.1155/2022/2789279The Correlation between Microalbuminuria and Thyroid Nodules in Type 2 Diabetic MellitusCan Cao0Zhao-Li Cui1Juan Miao2Jing-Xin Zhou3Xiao-Nan Wang4Jian Jin5Department of Nephrology and EndocrinologyDepartment of Nephrology and EndocrinologyDepartment of Nephrology and EndocrinologyDepartment of Nephrology and EndocrinologyDepartment of Nephrology and EndocrinologyDepartment of Nephrology and EndocrinologyObjective. To investigate the correlation between thyroid nodules and microalbuminuria in type 2 diabetic mellitus. Methods. A total of 270 patients with type 2 diabetes at Tongzhou Branch of Dongzhimen Hospital were enrolled in this retrospective study. Data were collected from the inpatient electronic files between January 2018 and January 2020. The laboratory indexes of the two groups (thyroid nodule group with 172 cases and control group including 98 cases without thyroid nodules) were statistically analyzed by binomial logistic regression analysis and Spearman correlation analysis. Results. The proportion of microalbuminuria (MAU) in the thyroid nodule group was larger than that in the control group. Age, serum TT4, and FT4 in the thyroid nodule group were significantly higher compared with the control group. The binary logistic regression analysis indicated that age, sex, FT4, and MAU were the risk factors for thyroid nodule in T2DM patients. Spearman correlation analysis showed that the thyroid nodule was significantly positively correlated with MAU, age, FT4, and TT4. Conclusions. MAU might be an independent risk factor for thyroid nodule in type 2 diabetic mellitus.http://dx.doi.org/10.1155/2022/2789279
spellingShingle Can Cao
Zhao-Li Cui
Juan Miao
Jing-Xin Zhou
Xiao-Nan Wang
Jian Jin
The Correlation between Microalbuminuria and Thyroid Nodules in Type 2 Diabetic Mellitus
International Journal of Endocrinology
title The Correlation between Microalbuminuria and Thyroid Nodules in Type 2 Diabetic Mellitus
title_full The Correlation between Microalbuminuria and Thyroid Nodules in Type 2 Diabetic Mellitus
title_fullStr The Correlation between Microalbuminuria and Thyroid Nodules in Type 2 Diabetic Mellitus
title_full_unstemmed The Correlation between Microalbuminuria and Thyroid Nodules in Type 2 Diabetic Mellitus
title_short The Correlation between Microalbuminuria and Thyroid Nodules in Type 2 Diabetic Mellitus
title_sort correlation between microalbuminuria and thyroid nodules in type 2 diabetic mellitus
url http://dx.doi.org/10.1155/2022/2789279
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