Perivascular Wall Tumor in the Brain of a Dog
A 9-year-old spayed female German shepherd mixed-breed dog presented for seizures. Magnetic resonance imaging revealed an irregularly marginated intraparenchymal cerebral mass. Microscopic examination of brain tissue collected postmortem demonstrated perivascular whorling and interwoven bundles of s...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Case Reports in Veterinary Medicine |
| Online Access: | http://dx.doi.org/10.1155/2015/725985 |
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| _version_ | 1832563792280551424 |
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| author | Margaret Cohn-Urbach Annie Chen Gary Haldorson Stephanie Thomovsky |
| author_facet | Margaret Cohn-Urbach Annie Chen Gary Haldorson Stephanie Thomovsky |
| author_sort | Margaret Cohn-Urbach |
| collection | DOAJ |
| description | A 9-year-old spayed female German shepherd mixed-breed dog presented for seizures. Magnetic resonance imaging revealed an irregularly marginated intraparenchymal cerebral mass. Microscopic examination of brain tissue collected postmortem demonstrated perivascular whorling and interwoven bundles of spindle-shaped cells. On immunohistochemistry, the tumor cells tested positive for vimentin and negative for factor VIII-related antigen, CD18, CD45, CD3, CD20, GFAP, S-100, and desmin. Immunohistochemistry results, in combination with histopathologic morphology, were suggestive of a perivascular wall tumor. To the authors’ knowledge, this is the first case report to utilize both histopathology and immunohistochemistry to describe a perivascular wall tumor in the brain of a dog. |
| format | Article |
| id | doaj-art-8eaad8e11bbd400bb8434bb19848fe89 |
| institution | Kabale University |
| issn | 2090-7001 2090-701X |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Veterinary Medicine |
| spelling | doaj-art-8eaad8e11bbd400bb8434bb19848fe892025-02-03T01:12:33ZengWileyCase Reports in Veterinary Medicine2090-70012090-701X2015-01-01201510.1155/2015/725985725985Perivascular Wall Tumor in the Brain of a DogMargaret Cohn-Urbach0Annie Chen1Gary Haldorson2Stephanie Thomovsky3Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Washington State University, P.O. Box 647010, Pullman, WA 99164-7010, USADepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, Washington State University, P.O. Box 647010, Pullman, WA 99164-7010, USADepartment of Veterinary Microbiology and Pathology, College of Veterinary Medicine, Washington State University, P.O. Box 647040, Pullman, WA 99164-7040, USADepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, Purdue University, 625 Harrison Street, West Lafayette, IN 47907-2026, USAA 9-year-old spayed female German shepherd mixed-breed dog presented for seizures. Magnetic resonance imaging revealed an irregularly marginated intraparenchymal cerebral mass. Microscopic examination of brain tissue collected postmortem demonstrated perivascular whorling and interwoven bundles of spindle-shaped cells. On immunohistochemistry, the tumor cells tested positive for vimentin and negative for factor VIII-related antigen, CD18, CD45, CD3, CD20, GFAP, S-100, and desmin. Immunohistochemistry results, in combination with histopathologic morphology, were suggestive of a perivascular wall tumor. To the authors’ knowledge, this is the first case report to utilize both histopathology and immunohistochemistry to describe a perivascular wall tumor in the brain of a dog.http://dx.doi.org/10.1155/2015/725985 |
| spellingShingle | Margaret Cohn-Urbach Annie Chen Gary Haldorson Stephanie Thomovsky Perivascular Wall Tumor in the Brain of a Dog Case Reports in Veterinary Medicine |
| title | Perivascular Wall Tumor in the Brain of a Dog |
| title_full | Perivascular Wall Tumor in the Brain of a Dog |
| title_fullStr | Perivascular Wall Tumor in the Brain of a Dog |
| title_full_unstemmed | Perivascular Wall Tumor in the Brain of a Dog |
| title_short | Perivascular Wall Tumor in the Brain of a Dog |
| title_sort | perivascular wall tumor in the brain of a dog |
| url | http://dx.doi.org/10.1155/2015/725985 |
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