Relationship between Experimental Diet in Rats and Nonalcoholic Hepatic Disease: Review of Literature
Background. The pathophysiology of nonalcoholic fatty liver disease (NAFLD) is related to unhealthy lifestyles that combine sedentary lifestyle, hypercaloric diets, excessive saturated fats, refined carbohydrates, and high intake of fructose as a food additive to various processed products. Both the...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | International Journal of Hepatology |
| Online Access: | http://dx.doi.org/10.1155/2018/9023027 |
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| _version_ | 1832554720486490112 |
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| author | Ayane A. Rodrigues Raíssa S. B. Andrade Daniel F. P. Vasconcelos |
| author_facet | Ayane A. Rodrigues Raíssa S. B. Andrade Daniel F. P. Vasconcelos |
| author_sort | Ayane A. Rodrigues |
| collection | DOAJ |
| description | Background. The pathophysiology of nonalcoholic fatty liver disease (NAFLD) is related to unhealthy lifestyles that combine sedentary lifestyle, hypercaloric diets, excessive saturated fats, refined carbohydrates, and high intake of fructose as a food additive to various processed products. Both the broader recognition of the disease and the additional efforts to elucidate the NAFLD pathogenesis have led to an increase in animal models in recent years. Objective. This review was performed to provide better understanding of the association between the NAFLD and animal models. Methods. The search in the literature occurred before May of 2018 in the PUBMED database. Results. Most studies investigating the influence of diet on liver fat content have been performed using a high-calorie diet that leads to a significant increase in fat content in the liver. Conclusion. The findings of this review show that diet is one of the factors that predisposes to the appearance of NAFLD and that the studies presented a wide variety of designs. |
| format | Article |
| id | doaj-art-8e94af7868844a7b9942bc5c7293d449 |
| institution | Kabale University |
| issn | 2090-3448 2090-3456 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Hepatology |
| spelling | doaj-art-8e94af7868844a7b9942bc5c7293d4492025-02-03T05:50:46ZengWileyInternational Journal of Hepatology2090-34482090-34562018-01-01201810.1155/2018/90230279023027Relationship between Experimental Diet in Rats and Nonalcoholic Hepatic Disease: Review of LiteratureAyane A. Rodrigues0Raíssa S. B. Andrade1Daniel F. P. Vasconcelos2Postgraduate Program in Biomedical Sciences, Federal University of Piaui, Parnaiba, PI, BrazilPostgraduate Program in Biotechnology, Federal University of Piaui, Parniba, PI, BrazilPostgraduate Program in Biomedical Sciences, Federal University of Piaui, Parnaiba, PI, BrazilBackground. The pathophysiology of nonalcoholic fatty liver disease (NAFLD) is related to unhealthy lifestyles that combine sedentary lifestyle, hypercaloric diets, excessive saturated fats, refined carbohydrates, and high intake of fructose as a food additive to various processed products. Both the broader recognition of the disease and the additional efforts to elucidate the NAFLD pathogenesis have led to an increase in animal models in recent years. Objective. This review was performed to provide better understanding of the association between the NAFLD and animal models. Methods. The search in the literature occurred before May of 2018 in the PUBMED database. Results. Most studies investigating the influence of diet on liver fat content have been performed using a high-calorie diet that leads to a significant increase in fat content in the liver. Conclusion. The findings of this review show that diet is one of the factors that predisposes to the appearance of NAFLD and that the studies presented a wide variety of designs.http://dx.doi.org/10.1155/2018/9023027 |
| spellingShingle | Ayane A. Rodrigues Raíssa S. B. Andrade Daniel F. P. Vasconcelos Relationship between Experimental Diet in Rats and Nonalcoholic Hepatic Disease: Review of Literature International Journal of Hepatology |
| title | Relationship between Experimental Diet in Rats and Nonalcoholic Hepatic Disease: Review of Literature |
| title_full | Relationship between Experimental Diet in Rats and Nonalcoholic Hepatic Disease: Review of Literature |
| title_fullStr | Relationship between Experimental Diet in Rats and Nonalcoholic Hepatic Disease: Review of Literature |
| title_full_unstemmed | Relationship between Experimental Diet in Rats and Nonalcoholic Hepatic Disease: Review of Literature |
| title_short | Relationship between Experimental Diet in Rats and Nonalcoholic Hepatic Disease: Review of Literature |
| title_sort | relationship between experimental diet in rats and nonalcoholic hepatic disease review of literature |
| url | http://dx.doi.org/10.1155/2018/9023027 |
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