Global existence and uniqueness of classical solutions for a generalized quasilinear parabolic equation with application to a glioblastoma growth model
This paper studies the global existence and uniqueness of classicalsolutions for a generalized quasilinear parabolic equation withappropriate initial and mixed boundary conditions. Under somepracticable regularity criteria on diffusion item and nonlinearity, weestablish the local existence and uniqu...
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Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
AIMS Press
2017-03-01
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Series: | Mathematical Biosciences and Engineering |
Subjects: | |
Online Access: | https://www.aimspress.com/article/doi/10.3934/mbe.2017025 |
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Summary: | This paper studies the global existence and uniqueness of classicalsolutions for a generalized quasilinear parabolic equation withappropriate initial and mixed boundary conditions. Under somepracticable regularity criteria on diffusion item and nonlinearity, weestablish the local existence and uniqueness of classical solutionsbased on a contraction mapping. This local solution can be continuedfor all positive time by employing the methods of energy estimates, $ L^{p} $-theory, and Schauder estimate of linear parabolic equations. Astraightforward application of global existence result of classical solutions to a density-dependent diffusion model of in vitroglioblastoma growth is also presented. |
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ISSN: | 1551-0018 |