Diverse Presentation of Breath Holding Spells: Two Case Reports with Literature Review

Breath holding spells are a common and dramatic form of syncope and anoxic seizure in infancy. They are usually triggered by an emotional stimuli or minor trauma. Based on the color change, they are classified into 3 types, cyanotic, pallid, and mixed. Pallid breath holding spells result from exagge...

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Main Authors: Geetanjali Rathore, Paul Larsen, Cristina Fernandez, Manish Parakh
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Case Reports in Neurological Medicine
Online Access:http://dx.doi.org/10.1155/2013/603190
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author Geetanjali Rathore
Paul Larsen
Cristina Fernandez
Manish Parakh
author_facet Geetanjali Rathore
Paul Larsen
Cristina Fernandez
Manish Parakh
author_sort Geetanjali Rathore
collection DOAJ
description Breath holding spells are a common and dramatic form of syncope and anoxic seizure in infancy. They are usually triggered by an emotional stimuli or minor trauma. Based on the color change, they are classified into 3 types, cyanotic, pallid, and mixed. Pallid breath holding spells result from exaggerated, vagally-mediated cardiac inhibition, whereas the more common, cyanotic breathholding spells are of more complex pathogenesis which is not completely understood. A detailed and accurate history is the mainstay of diagnosis. An EKG should be strongly considered to rule out long QT syndrome. Spontaneous resolution of breath-holding spells is usually seen, without any adverse developmental and intellectual sequelae. Rare cases of status epilepticus, prolonged asystole, and sudden death have been reported. Reassurance and education is the mainstay of therapy. Occasionally, pharmacologic intervention with iron, piracetam; atropine may be of benefit. Here we present 2 cases, one of each, pallid and cyanotic breath holding spells.
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institution Kabale University
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spelling doaj-art-8e3d8ef8702f4b26a7f1732ed12afb7c2025-02-03T01:10:05ZengWileyCase Reports in Neurological Medicine2090-66682090-66762013-01-01201310.1155/2013/603190603190Diverse Presentation of Breath Holding Spells: Two Case Reports with Literature ReviewGeetanjali Rathore0Paul Larsen1Cristina Fernandez2Manish Parakh3Pediatric Neurology, Baylor College of Medicine, Houston, TX 77030, USAPediatric Neurology, University of Nebraska Medical Center, Omaha, NE 68198, USAPediatrics, Creighton University, Omaha, NE 68131, USAPediatric Neurology, Umaid Women and Children’s Hospital, Jodhpur, Rajasthan 342001, IndiaBreath holding spells are a common and dramatic form of syncope and anoxic seizure in infancy. They are usually triggered by an emotional stimuli or minor trauma. Based on the color change, they are classified into 3 types, cyanotic, pallid, and mixed. Pallid breath holding spells result from exaggerated, vagally-mediated cardiac inhibition, whereas the more common, cyanotic breathholding spells are of more complex pathogenesis which is not completely understood. A detailed and accurate history is the mainstay of diagnosis. An EKG should be strongly considered to rule out long QT syndrome. Spontaneous resolution of breath-holding spells is usually seen, without any adverse developmental and intellectual sequelae. Rare cases of status epilepticus, prolonged asystole, and sudden death have been reported. Reassurance and education is the mainstay of therapy. Occasionally, pharmacologic intervention with iron, piracetam; atropine may be of benefit. Here we present 2 cases, one of each, pallid and cyanotic breath holding spells.http://dx.doi.org/10.1155/2013/603190
spellingShingle Geetanjali Rathore
Paul Larsen
Cristina Fernandez
Manish Parakh
Diverse Presentation of Breath Holding Spells: Two Case Reports with Literature Review
Case Reports in Neurological Medicine
title Diverse Presentation of Breath Holding Spells: Two Case Reports with Literature Review
title_full Diverse Presentation of Breath Holding Spells: Two Case Reports with Literature Review
title_fullStr Diverse Presentation of Breath Holding Spells: Two Case Reports with Literature Review
title_full_unstemmed Diverse Presentation of Breath Holding Spells: Two Case Reports with Literature Review
title_short Diverse Presentation of Breath Holding Spells: Two Case Reports with Literature Review
title_sort diverse presentation of breath holding spells two case reports with literature review
url http://dx.doi.org/10.1155/2013/603190
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