A Fractional Epidemiological Model for Bone Remodeling Process

This article focuses on modeling bone formation process using a fractional differential approach, named bones remodeling process. The first goal of the work is to investigate existence and uniqueness of the proposed fractional differential model. The next goal is to investigate how similar is the pr...

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Main Authors: Muath Awadalla, Yves Yannick Yameni Noupoue, Kinda Abuasbeh
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Journal of Mathematics
Online Access:http://dx.doi.org/10.1155/2021/1614774
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author Muath Awadalla
Yves Yannick Yameni Noupoue
Kinda Abuasbeh
author_facet Muath Awadalla
Yves Yannick Yameni Noupoue
Kinda Abuasbeh
author_sort Muath Awadalla
collection DOAJ
description This article focuses on modeling bone formation process using a fractional differential approach, named bones remodeling process. The first goal of the work is to investigate existence and uniqueness of the proposed fractional differential model. The next goal is to investigate how similar is the proposed approach to the method based on system classical differential equations. The dynamical system of equations used is built upon three main parameters. These are chemical substances, namely, calcitonin secretion, osteoclastic and osteoblastic, which are involved in the bone’s formation process. We implement some numerical simulations to graphically show the impact of an arbitrary fractional order of derivative. We finally obtained that modeling bone formation process using fractional differential equations yielded comparable results with those obtained through a system of classical differential equations. Flexibility in the choice of the fractional order of derivative is an advantage as it helps in selecting the best fractional order of derivative.
format Article
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institution Kabale University
issn 2314-4785
language English
publishDate 2021-01-01
publisher Wiley
record_format Article
series Journal of Mathematics
spelling doaj-art-8e3b1719b6ab46af9ac26aed6b3f238a2025-02-03T01:01:06ZengWileyJournal of Mathematics2314-47852021-01-01202110.1155/2021/1614774A Fractional Epidemiological Model for Bone Remodeling ProcessMuath Awadalla0Yves Yannick Yameni Noupoue1Kinda Abuasbeh2Department of Mathematics and StatisticsInstitute of Statistics, Biostatistics and Actuarial Sciences (ISBA)Department of Mathematics and StatisticsThis article focuses on modeling bone formation process using a fractional differential approach, named bones remodeling process. The first goal of the work is to investigate existence and uniqueness of the proposed fractional differential model. The next goal is to investigate how similar is the proposed approach to the method based on system classical differential equations. The dynamical system of equations used is built upon three main parameters. These are chemical substances, namely, calcitonin secretion, osteoclastic and osteoblastic, which are involved in the bone’s formation process. We implement some numerical simulations to graphically show the impact of an arbitrary fractional order of derivative. We finally obtained that modeling bone formation process using fractional differential equations yielded comparable results with those obtained through a system of classical differential equations. Flexibility in the choice of the fractional order of derivative is an advantage as it helps in selecting the best fractional order of derivative.http://dx.doi.org/10.1155/2021/1614774
spellingShingle Muath Awadalla
Yves Yannick Yameni Noupoue
Kinda Abuasbeh
A Fractional Epidemiological Model for Bone Remodeling Process
Journal of Mathematics
title A Fractional Epidemiological Model for Bone Remodeling Process
title_full A Fractional Epidemiological Model for Bone Remodeling Process
title_fullStr A Fractional Epidemiological Model for Bone Remodeling Process
title_full_unstemmed A Fractional Epidemiological Model for Bone Remodeling Process
title_short A Fractional Epidemiological Model for Bone Remodeling Process
title_sort fractional epidemiological model for bone remodeling process
url http://dx.doi.org/10.1155/2021/1614774
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AT yvesyannickyameninoupoue afractionalepidemiologicalmodelforboneremodelingprocess
AT kindaabuasbeh afractionalepidemiologicalmodelforboneremodelingprocess
AT muathawadalla fractionalepidemiologicalmodelforboneremodelingprocess
AT yvesyannickyameninoupoue fractionalepidemiologicalmodelforboneremodelingprocess
AT kindaabuasbeh fractionalepidemiologicalmodelforboneremodelingprocess