Coronary Microvascular Dysfunction: Insights on Prognosis and Future Perspectives
Coronary microvascular dysfunction (CMD) comprises a wide spectrum of structural and/or functional abnormalities of coronary microcirculation that can lead to myocardial ischemia. Emerging evidence has indicated that CMD is a relevant cause of morbidity and mortality and is associated with a high ri...
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| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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IMR Press
2025-01-01
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| Series: | Reviews in Cardiovascular Medicine |
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| Online Access: | https://www.imrpress.com/journal/RCM/26/1/10.31083/RCM25757 |
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| _version_ | 1832586520392892416 |
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| author | Filippo Luca Gurgoglione Giorgio Benatti Andrea Denegri Davide Donelli Marco Covani Mattia De Gregorio Gabriella Dallaglio Rebecca Navacchi Giampaolo Niccoli |
| author_facet | Filippo Luca Gurgoglione Giorgio Benatti Andrea Denegri Davide Donelli Marco Covani Mattia De Gregorio Gabriella Dallaglio Rebecca Navacchi Giampaolo Niccoli |
| author_sort | Filippo Luca Gurgoglione |
| collection | DOAJ |
| description | Coronary microvascular dysfunction (CMD) comprises a wide spectrum of structural and/or functional abnormalities of coronary microcirculation that can lead to myocardial ischemia. Emerging evidence has indicated that CMD is a relevant cause of morbidity and mortality and is associated with a high risk of major adverse cardiovascular events (MACEs) and heart failure with preserved ejection fraction as well as poor quality of life. This review aims to elucidate briefly the pathogenesis and diagnostic modalities of CMD and to shed light on contemporary evidence on the prognostic impact of CMD. Finally, we will provide an overview of novel emerging therapeutic strategies for CMD. |
| format | Article |
| id | doaj-art-8e1ac08b56ba453bbf02f7afb33d3fd4 |
| institution | Kabale University |
| issn | 1530-6550 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | IMR Press |
| record_format | Article |
| series | Reviews in Cardiovascular Medicine |
| spelling | doaj-art-8e1ac08b56ba453bbf02f7afb33d3fd42025-01-25T10:41:20ZengIMR PressReviews in Cardiovascular Medicine1530-65502025-01-012612575710.31083/RCM25757S1530-6550(24)01623-5Coronary Microvascular Dysfunction: Insights on Prognosis and Future PerspectivesFilippo Luca Gurgoglione0Giorgio Benatti1Andrea Denegri2Davide Donelli3Marco Covani4Mattia De Gregorio5Gabriella Dallaglio6Rebecca Navacchi7Giampaolo Niccoli8Division of Cardiology, University of Parma, Parma University Hospital, 14 - 43126 Parma, ItalyDivision of Cardiology, Parma University Hospital, 14 - 43126 Parma, ItalyDivision of Cardiology, Parma University Hospital, 14 - 43126 Parma, ItalyDivision of Cardiology, University of Parma, Parma University Hospital, 14 - 43126 Parma, ItalyDivision of Cardiology, University of Parma, Parma University Hospital, 14 - 43126 Parma, ItalyDivision of Cardiology, University of Parma, Parma University Hospital, 14 - 43126 Parma, ItalyDivision of Cardiology, University of Parma, Parma University Hospital, 14 - 43126 Parma, ItalyDivision of Cardiology, University of Parma, Parma University Hospital, 14 - 43126 Parma, ItalyDivision of Cardiology, University of Parma, Parma University Hospital, 14 - 43126 Parma, ItalyCoronary microvascular dysfunction (CMD) comprises a wide spectrum of structural and/or functional abnormalities of coronary microcirculation that can lead to myocardial ischemia. Emerging evidence has indicated that CMD is a relevant cause of morbidity and mortality and is associated with a high risk of major adverse cardiovascular events (MACEs) and heart failure with preserved ejection fraction as well as poor quality of life. This review aims to elucidate briefly the pathogenesis and diagnostic modalities of CMD and to shed light on contemporary evidence on the prognostic impact of CMD. Finally, we will provide an overview of novel emerging therapeutic strategies for CMD.https://www.imrpress.com/journal/RCM/26/1/10.31083/RCM25757coronary microvascular dysfunctionmajor adverse cardiovascular eventsheart failure with preserved ejection fractionquality of life |
| spellingShingle | Filippo Luca Gurgoglione Giorgio Benatti Andrea Denegri Davide Donelli Marco Covani Mattia De Gregorio Gabriella Dallaglio Rebecca Navacchi Giampaolo Niccoli Coronary Microvascular Dysfunction: Insights on Prognosis and Future Perspectives Reviews in Cardiovascular Medicine coronary microvascular dysfunction major adverse cardiovascular events heart failure with preserved ejection fraction quality of life |
| title | Coronary Microvascular Dysfunction: Insights on Prognosis and Future Perspectives |
| title_full | Coronary Microvascular Dysfunction: Insights on Prognosis and Future Perspectives |
| title_fullStr | Coronary Microvascular Dysfunction: Insights on Prognosis and Future Perspectives |
| title_full_unstemmed | Coronary Microvascular Dysfunction: Insights on Prognosis and Future Perspectives |
| title_short | Coronary Microvascular Dysfunction: Insights on Prognosis and Future Perspectives |
| title_sort | coronary microvascular dysfunction insights on prognosis and future perspectives |
| topic | coronary microvascular dysfunction major adverse cardiovascular events heart failure with preserved ejection fraction quality of life |
| url | https://www.imrpress.com/journal/RCM/26/1/10.31083/RCM25757 |
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