Follicular Regulatory T Cells in Systemic Lupus Erythematosus
Follicular regulatory T (Tfr) cells are the regulatory T cell subset mainly localized in the germinal center (GC), acting as modulators of GC responses. They can disrupt Tfh cell- and B cell-linked recognition, induce Tfh apoptosis, and suppress B cell function. Evidences show that dysregulated Tfr...
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Main Authors: | Xin Xia, Jun Yang, Shengjun Wang |
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Format: | Article |
Language: | English |
Published: |
Wiley
2021-01-01
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Series: | Journal of Immunology Research |
Online Access: | http://dx.doi.org/10.1155/2021/9943743 |
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