The repertoire of heavy chain immunoglobulin genes in B‑cell chronic lymphocytic leukemia in Russia and Belarus

The repertoire of heavy chain immunoglobulin genes in B‑cell chronic lymphocytic leukemia in Russia and Belarus

Mutation status of the heavy chain variable region genes has long been known as an important factor in long‑term prognosis in B‑cell chronic lymphocytic leukemia (B‑CLL). A more detailed study of the gene sequences of immunoglobulin heavy chain (IgVH) led to the discovery of stereotyped antigen rece...

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Bibliographic Details
Main Authors: B. V. Biderman, E. A. Nikitin, T. F. Sergienko, A. V. Bakun, L. B. Taras, A. I. Svirnovskiy, A. B. Sudarikov
Format: Article
Language:Russian
Published: ABV-press 2014-07-01
Series:Онкогематология
Subjects:
cll
igvh gene repertoir
mutation status
stereotyped antigen receptors
Online Access:https://oncohematology.abvpress.ru/ongm/article/view/52
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