Probing Wnt pathway and functional signal in equine melanocytic neoplasms through quantitative proteomics and immunohistochemistry

Probing Wnt pathway and functional signal in equine melanocytic neoplasms through quantitative proteomics and immunohistochemistry

Abstract Background Equine melanocytic neoplasm (EMN) is a skin tumor commonly observed in grey horses. Limited research has yet to investigate proteomic profiles of EMN, particularly in the early stages and their expression patterns. This study, therefore, aimed to identify signature proteins from...

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Main Authors: Parichart Tesena, Ruethaiwan Vinijkumthorn, Amornthep Kingkaw, Petchpailin Yanyongsirikarn, Khajornpol Phasuk, Sekkarin Ploypetch, Narumon Phaonakrop, Sittiruk Roytrakul, Wanwipa Vongsangnak, Nawarus Prapaiwan
Format: Article
Language:English
Published: BMC 2025-08-01
Series:BMC Veterinary Research
Subjects:
Equine melanocytic neoplasm
Grey horses
Immunohistochemistry
Proteomics
Wnt pathway
Online Access:https://doi.org/10.1186/s12917-025-04956-w
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