PET imaging of HIV-1 envelope protein gp120 using 18F-labeled nanobodies

PET imaging of HIV-1 envelope protein gp120 using 18F-labeled nanobodies

Summary: Radiolabeled antibodies against the HIV-1 envelope protein, gp120, have been previously tested in animal models and in people with HIV (PWH). Nanobodies offer advantages over antibodies, including smaller size and faster clearance, which allow labeling with fluorine-18. In this study, three...

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Bibliographic Details
Main Authors: Neysha Martinez-Orengo, Swati Shah, Jianhao Lai, Falguni Basuli, Anna Lyndaker, Mitchell L. Turner, Morteza Peiravi, Suman Sourabh, Kevon Sampson, Peng Zhang, Rolf E. Swenson, Paolo Lusso, Frank Maldarelli, Avindra Nath, Chuen-Yen Lau, Dima A. Hammoud
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:iScience
Subjects:
Immunology
Radiology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004225000549
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