Nano-encapsulated active protein AMPK inhibits cartilage matrix degradation in experimental osteoarthritis rats via SIRT1-regulated nexilin expression nano-AMPK inhibits cartilage matrix degradation
Background: Osteoarthritis (OA) is characterized by progressive cartilage matrix degradation. Although adenosine monophosphate-activated protein kinase (AMPK) shows promise in treating OA, its clinical application is limited by poor bioavailability. Nano-encapsulation may overcome this limitation, b...
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| Main Authors: | X You, LQ Wu, LL Fu, QQ Wu, BR Qi |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Forum Multimedia Publishing LLC
2025-04-01
|
| Series: | European Cells & Materials |
| Subjects: | |
| Online Access: | https://www.ecmjournal.org/papers/vol050/vol050a07.php |
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