Potentiation of Antidepressant Effects of Agomelatine and Bupropion by Hesperidin in Mice
Hesperidin, a well-known flavanone glycoside mostly found in citrus fruits, showed neuroprotective and antidepressant activity. Agomelatine, a melatonergic MT1/MT2 agonist and 5-HT2C receptor antagonist, exhibits good antidepressant efficacy. Bupropion has been widely used for the treatment of depre...
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Main Authors: | Jegan Sakthivel Nadar, Pravin Popatrao Kale, Pramod Kerunath Kadu, Kedar Prabhavalkar, Ruchita Dhangar |
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Format: | Article |
Language: | English |
Published: |
Wiley
2018-01-01
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Series: | Neurology Research International |
Online Access: | http://dx.doi.org/10.1155/2018/9828639 |
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