Successful Treatment of Opioid Dependence with Flexible Doses of Injectable Prolonged Release Buprenorphine
Opioid dependence (OD) may be effectively treated with well-evidenced regimens including psychosocial and pharmacotherapeutic interventions. Treatment has benefits but also limitations including risk of diversion, impact of mandatory daily supervision, and stigma. An injectable prolonged release bup...
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| Format: | Article |
| Language: | English |
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Wiley
2019-01-01
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| Series: | Case Reports in Psychiatry |
| Online Access: | http://dx.doi.org/10.1155/2019/9381346 |
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| author | Oscar D’Agnone |
| author_facet | Oscar D’Agnone |
| author_sort | Oscar D’Agnone |
| collection | DOAJ |
| description | Opioid dependence (OD) may be effectively treated with well-evidenced regimens including psychosocial and pharmacotherapeutic interventions. Treatment has benefits but also limitations including risk of diversion, impact of mandatory daily supervision, and stigma. An injectable prolonged release buprenorphine with flexible dose options has recently been approved by the European Commission and is available in the UK and other European Countries. Initial positive treatment experience in patients with different clinical scenarios (patients with no recent treatment history, a transfer from oral methadone, and change from sublingual buprenorphine tablets) provides evidence of the potential benefit in a range of situations for this therapeutic option. Adoption of the injectable form was clinically successful with no withdrawal signs, nor evidence of use of other drugs. Patient reported outcomes were positive including reduction in cravings and anxiety and improved attitude, relationships, and general mood. |
| format | Article |
| id | doaj-art-8dbffe1a67ca4d59a49168b20f2a193a |
| institution | Kabale University |
| issn | 2090-682X 2090-6838 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Psychiatry |
| spelling | doaj-art-8dbffe1a67ca4d59a49168b20f2a193a2025-02-03T01:11:11ZengWileyCase Reports in Psychiatry2090-682X2090-68382019-01-01201910.1155/2019/93813469381346Successful Treatment of Opioid Dependence with Flexible Doses of Injectable Prolonged Release BuprenorphineOscar D’Agnone0The OAD Clinic, London, UKOpioid dependence (OD) may be effectively treated with well-evidenced regimens including psychosocial and pharmacotherapeutic interventions. Treatment has benefits but also limitations including risk of diversion, impact of mandatory daily supervision, and stigma. An injectable prolonged release buprenorphine with flexible dose options has recently been approved by the European Commission and is available in the UK and other European Countries. Initial positive treatment experience in patients with different clinical scenarios (patients with no recent treatment history, a transfer from oral methadone, and change from sublingual buprenorphine tablets) provides evidence of the potential benefit in a range of situations for this therapeutic option. Adoption of the injectable form was clinically successful with no withdrawal signs, nor evidence of use of other drugs. Patient reported outcomes were positive including reduction in cravings and anxiety and improved attitude, relationships, and general mood.http://dx.doi.org/10.1155/2019/9381346 |
| spellingShingle | Oscar D’Agnone Successful Treatment of Opioid Dependence with Flexible Doses of Injectable Prolonged Release Buprenorphine Case Reports in Psychiatry |
| title | Successful Treatment of Opioid Dependence with Flexible Doses of Injectable Prolonged Release Buprenorphine |
| title_full | Successful Treatment of Opioid Dependence with Flexible Doses of Injectable Prolonged Release Buprenorphine |
| title_fullStr | Successful Treatment of Opioid Dependence with Flexible Doses of Injectable Prolonged Release Buprenorphine |
| title_full_unstemmed | Successful Treatment of Opioid Dependence with Flexible Doses of Injectable Prolonged Release Buprenorphine |
| title_short | Successful Treatment of Opioid Dependence with Flexible Doses of Injectable Prolonged Release Buprenorphine |
| title_sort | successful treatment of opioid dependence with flexible doses of injectable prolonged release buprenorphine |
| url | http://dx.doi.org/10.1155/2019/9381346 |
| work_keys_str_mv | AT oscardagnone successfultreatmentofopioiddependencewithflexibledosesofinjectableprolongedreleasebuprenorphine |