Vaccination with synthetic long peptide and CpG 2395 in AddaVax induces potent anti-tumor effects

Vaccination with synthetic long peptide and CpG 2395 in AddaVax induces potent anti-tumor effects

Cancer/testis antigen HCA587, also known as MAGE-C2, highly expressed in a wide range of malignant tumors with unique immunological characteristics, serves as a potential target for tumor immunotherapy. Synthetic long peptides from HCA587 (HCA587 SLP) were proved to be highly immunogenic and promisi...

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Bibliographic Details
Main Authors: Shanshan Jiang, Shuqi Zhao, Qiaojiajie Zhao, Yinfang Wang, Weihua Zhang, Yangmeng Feng, Lijie Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Experimental Biology and Medicine
Subjects:
AddaVax
synthetic long peptides
vaccine
anti-tumor effects
CpG 2395
Online Access:https://www.ebm-journal.org/articles/10.3389/ebm.2025.10509/full
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