Harnessing nanotechnology for cancer treatment
Nanotechnology has become a groundbreaking innovation force in cancer therapy, offering innovative solutions to the limitations of conventional treatments such as chemotherapy and radiation. By manipulating materials at the nanoscale, researchers have developed nanocarriers capable of targeted drug...
Saved in:
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-01-01
|
| Series: | Frontiers in Bioengineering and Biotechnology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fbioe.2024.1514890/full |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832593943066312704 |
|---|---|
| author | Jiajun Zhu Jiajun Zhu HaeJu Lee HaeJu Lee Ruotong Huang Ruotong Huang Jianming Zhou Jingjun Zhang Xiaoyi Yang Wenhan Zhou Wangqing Jiang Shuying Chen |
| author_facet | Jiajun Zhu Jiajun Zhu HaeJu Lee HaeJu Lee Ruotong Huang Ruotong Huang Jianming Zhou Jingjun Zhang Xiaoyi Yang Wenhan Zhou Wangqing Jiang Shuying Chen |
| author_sort | Jiajun Zhu |
| collection | DOAJ |
| description | Nanotechnology has become a groundbreaking innovation force in cancer therapy, offering innovative solutions to the limitations of conventional treatments such as chemotherapy and radiation. By manipulating materials at the nanoscale, researchers have developed nanocarriers capable of targeted drug delivery, improving therapeutic efficacy while reducing systemic toxicity. Nanoparticles like liposomes, dendrimers, and polymeric nanomaterials have shown significant promise in delivering chemotherapeutic agents directly to tumor sites, enhancing drug bioavailability and minimizing damage to healthy tissues. In addition to drug delivery, with the utilization of tools such as quantum dots and nanosensors that enables more precise identification of cancer biomarkers, nanotechnology is also playing a pivotal role in early cancer detection and diagnosis. Furthermore, nanotechnology-based therapeutic strategies, including photothermal therapy, gene therapy and immunotherapy are offering novel ways to combat cancer by selectively targeting tumor cells and enhancing the immune response. Nevertheless, despite these progressions, obstacles still persist, particularly in the clinical translation of these technologies. Issues such as nanoparticle toxicity, biocompatibility, and the complexity of regulatory approval hinder the widespread adoption of nanomedicine in oncology. This review discusses different applications of nanotechnology in cancer therapy, highlighting its potential and the hurdles to its clinical implementation. Future research needs to concentrate on addressing these obstacles to unlock the full potential of nanotechnology in providing personalized, effective, and minimally invasive cancer treatments. |
| format | Article |
| id | doaj-art-8d9ed2df659944f5b70b40f90e88e8bc |
| institution | Kabale University |
| issn | 2296-4185 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Bioengineering and Biotechnology |
| spelling | doaj-art-8d9ed2df659944f5b70b40f90e88e8bc2025-01-20T07:20:18ZengFrontiers Media S.A.Frontiers in Bioengineering and Biotechnology2296-41852025-01-011210.3389/fbioe.2024.15148901514890Harnessing nanotechnology for cancer treatmentJiajun Zhu0Jiajun Zhu1HaeJu Lee2HaeJu Lee3Ruotong Huang4Ruotong Huang5Jianming Zhou6Jingjun Zhang7Xiaoyi Yang8Wenhan Zhou9Wangqing Jiang10Shuying Chen11Department of Laboratory Medicine, Huashan Hospital, Fudan University, Shanghai, ChinaShanghai Medical College, Fudan University, Shanghai, ChinaDepartment of Laboratory Medicine, Huashan Hospital, Fudan University, Shanghai, ChinaShanghai Medical College, Fudan University, Shanghai, ChinaDepartment of Laboratory Medicine, Huashan Hospital, Fudan University, Shanghai, ChinaShanghai Medical College, Fudan University, Shanghai, ChinaShanghai Medical College, Fudan University, Shanghai, ChinaDepartment of Rehabilitation Medicine, The Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaShanghai Medical College, Fudan University, Shanghai, ChinaShanghai Medical College, Fudan University, Shanghai, ChinaDepartment of Laboratory Medicine, Huashan Hospital, Fudan University, Shanghai, ChinaDepartment of Laboratory Medicine, Huashan Hospital, Fudan University, Shanghai, ChinaNanotechnology has become a groundbreaking innovation force in cancer therapy, offering innovative solutions to the limitations of conventional treatments such as chemotherapy and radiation. By manipulating materials at the nanoscale, researchers have developed nanocarriers capable of targeted drug delivery, improving therapeutic efficacy while reducing systemic toxicity. Nanoparticles like liposomes, dendrimers, and polymeric nanomaterials have shown significant promise in delivering chemotherapeutic agents directly to tumor sites, enhancing drug bioavailability and minimizing damage to healthy tissues. In addition to drug delivery, with the utilization of tools such as quantum dots and nanosensors that enables more precise identification of cancer biomarkers, nanotechnology is also playing a pivotal role in early cancer detection and diagnosis. Furthermore, nanotechnology-based therapeutic strategies, including photothermal therapy, gene therapy and immunotherapy are offering novel ways to combat cancer by selectively targeting tumor cells and enhancing the immune response. Nevertheless, despite these progressions, obstacles still persist, particularly in the clinical translation of these technologies. Issues such as nanoparticle toxicity, biocompatibility, and the complexity of regulatory approval hinder the widespread adoption of nanomedicine in oncology. This review discusses different applications of nanotechnology in cancer therapy, highlighting its potential and the hurdles to its clinical implementation. Future research needs to concentrate on addressing these obstacles to unlock the full potential of nanotechnology in providing personalized, effective, and minimally invasive cancer treatments.https://www.frontiersin.org/articles/10.3389/fbioe.2024.1514890/fullnanotechnologycancer treatmenttargeted drug deliveryearly detectioncancer diagnosticstherapeutic strategies |
| spellingShingle | Jiajun Zhu Jiajun Zhu HaeJu Lee HaeJu Lee Ruotong Huang Ruotong Huang Jianming Zhou Jingjun Zhang Xiaoyi Yang Wenhan Zhou Wangqing Jiang Shuying Chen Harnessing nanotechnology for cancer treatment Frontiers in Bioengineering and Biotechnology nanotechnology cancer treatment targeted drug delivery early detection cancer diagnostics therapeutic strategies |
| title | Harnessing nanotechnology for cancer treatment |
| title_full | Harnessing nanotechnology for cancer treatment |
| title_fullStr | Harnessing nanotechnology for cancer treatment |
| title_full_unstemmed | Harnessing nanotechnology for cancer treatment |
| title_short | Harnessing nanotechnology for cancer treatment |
| title_sort | harnessing nanotechnology for cancer treatment |
| topic | nanotechnology cancer treatment targeted drug delivery early detection cancer diagnostics therapeutic strategies |
| url | https://www.frontiersin.org/articles/10.3389/fbioe.2024.1514890/full |
| work_keys_str_mv | AT jiajunzhu harnessingnanotechnologyforcancertreatment AT jiajunzhu harnessingnanotechnologyforcancertreatment AT haejulee harnessingnanotechnologyforcancertreatment AT haejulee harnessingnanotechnologyforcancertreatment AT ruotonghuang harnessingnanotechnologyforcancertreatment AT ruotonghuang harnessingnanotechnologyforcancertreatment AT jianmingzhou harnessingnanotechnologyforcancertreatment AT jingjunzhang harnessingnanotechnologyforcancertreatment AT xiaoyiyang harnessingnanotechnologyforcancertreatment AT wenhanzhou harnessingnanotechnologyforcancertreatment AT wangqingjiang harnessingnanotechnologyforcancertreatment AT shuyingchen harnessingnanotechnologyforcancertreatment |