Mitigation of epidemics in contact networks through optimal contact adaptation

This paper presents an optimal control problem formulation to minimize the total number of infection cases during the spread of susceptible-infected-recovered SIR epidemics in contact networks. In the new approach, contact weighted are reduced among nodes and a global minimum contact level is preser...

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Main Authors: Mina Youssef, Caterina Scoglio
Format: Article
Language:English
Published: AIMS Press 2013-05-01
Series:Mathematical Biosciences and Engineering
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Online Access:https://www.aimspress.com/article/doi/10.3934/mbe.2013.10.1227
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author Mina Youssef
Caterina Scoglio
author_facet Mina Youssef
Caterina Scoglio
author_sort Mina Youssef
collection DOAJ
description This paper presents an optimal control problem formulation to minimize the total number of infection cases during the spread of susceptible-infected-recovered SIR epidemics in contact networks. In the new approach, contact weighted are reduced among nodes and a global minimum contact level is preserved in the network. In addition, the infection cost and the cost associated with the contact reduction are linearly combined in a single objective function. Hence, the optimal control formulation addresses the tradeoff between minimization of total infection cases and minimization of contact weights reduction. Using Pontryagin theorem, the obtained solution is a unique candidate representing the dynamical weighted contact network. To find the near-optimal solution in a decentralized way, we propose two heuristics based on Bang-Bang control function and on a piecewise nonlinear control function, respectively. We perform extensive simulations to evaluate the two heuristics on different networks. Our results show that the piecewise nonlinear control function outperforms the well-known Bang-Bang control function in minimizing both the total number of infection cases and the reduction of contact weights. Finally, our results show awareness of the infection level at which the mitigation strategies are effectively applied to the contact weights.
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institution Kabale University
issn 1551-0018
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spelling doaj-art-8d9a6182085441e684691925464409ec2025-01-24T02:26:20ZengAIMS PressMathematical Biosciences and Engineering1551-00182013-05-011041227125110.3934/mbe.2013.10.1227Mitigation of epidemics in contact networks through optimal contact adaptationMina Youssef0Caterina Scoglio1K-State Epicenter, Department of Electrical and Computer Engineering, Kansas State University, 2061 Rathbone Hall, Manhattan, KS 66506-5204K-State Epicenter, Department of Electrical and Computer Engineering, Kansas State University, 2061 Rathbone Hall, Manhattan, KS 66506-5204This paper presents an optimal control problem formulation to minimize the total number of infection cases during the spread of susceptible-infected-recovered SIR epidemics in contact networks. In the new approach, contact weighted are reduced among nodes and a global minimum contact level is preserved in the network. In addition, the infection cost and the cost associated with the contact reduction are linearly combined in a single objective function. Hence, the optimal control formulation addresses the tradeoff between minimization of total infection cases and minimization of contact weights reduction. Using Pontryagin theorem, the obtained solution is a unique candidate representing the dynamical weighted contact network. To find the near-optimal solution in a decentralized way, we propose two heuristics based on Bang-Bang control function and on a piecewise nonlinear control function, respectively. We perform extensive simulations to evaluate the two heuristics on different networks. Our results show that the piecewise nonlinear control function outperforms the well-known Bang-Bang control function in minimizing both the total number of infection cases and the reduction of contact weights. Finally, our results show awareness of the infection level at which the mitigation strategies are effectively applied to the contact weights.https://www.aimspress.com/article/doi/10.3934/mbe.2013.10.1227spread of epidemicsnetwork-based approachbehavioral responses.adaptive contact networksoptimal control of epidemics
spellingShingle Mina Youssef
Caterina Scoglio
Mitigation of epidemics in contact networks through optimal contact adaptation
Mathematical Biosciences and Engineering
spread of epidemics
network-based approach
behavioral responses.
adaptive contact networks
optimal control of epidemics
title Mitigation of epidemics in contact networks through optimal contact adaptation
title_full Mitigation of epidemics in contact networks through optimal contact adaptation
title_fullStr Mitigation of epidemics in contact networks through optimal contact adaptation
title_full_unstemmed Mitigation of epidemics in contact networks through optimal contact adaptation
title_short Mitigation of epidemics in contact networks through optimal contact adaptation
title_sort mitigation of epidemics in contact networks through optimal contact adaptation
topic spread of epidemics
network-based approach
behavioral responses.
adaptive contact networks
optimal control of epidemics
url https://www.aimspress.com/article/doi/10.3934/mbe.2013.10.1227
work_keys_str_mv AT minayoussef mitigationofepidemicsincontactnetworksthroughoptimalcontactadaptation
AT caterinascoglio mitigationofepidemicsincontactnetworksthroughoptimalcontactadaptation