LL37 promotes angiogenesis: a potential therapeutic strategy for lower limb ischemic diseases
PurposeTo study the angiogenic capacity of antimicrobial peptide LL37 (cathelicidin antimicrobial peptide), explore its molecular mechanisms, and provide new ideas for treating lower limb ischemic diseases.MethodsLL37 was applied exogenously to human umbilical vein endothelial cells (HUVECs), and it...
Saved in:
| Main Authors: | Yingying Yang, Gang Wu, Yini Wang, Qiancheng Mao, Dongxu Zhang, Jitao Wu |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-04-01
|
| Series: | Frontiers in Pharmacology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fphar.2025.1587351/full |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
A positive feedback loop between mTORC1 and cathelicidin promotes skin inflammation in rosacea
by: Zhili Deng, et al.
Published: (2021-03-01) -
Glioblastoma Multiforme: Sensitivity to Antimicrobial Peptides LL-37 and PG-1, and Their Combination with Chemotherapy for Predicting the Overall Survival of Patients
by: Alexander N. Chernov, et al.
Published: (2024-09-01) -
Evaluation of Cathelicidin (LL-37) Serum Levels Among Iraqi Psoriatic Patients and Its Association with Disease Severity and Complications
by: Rasool Moussa Bader Al-asade, et al.
Published: (2025-06-01) -
LL-37 and citrullinated-LL-37 modulate IL-17A/F-mediated responses and selectively suppress Lipocalin-2 in bronchial epithelial cells
by: Anthony Altieri, et al.
Published: (2025-05-01) -
Vitamin D and LL-37 in Serum and Saliva: Insights into Oral Immunity
by: Sotiria Davidopoulou, et al.
Published: (2025-02-01)