A dual-gene panel of two fragments of methylated IRF4 and one of ZEB2 in plasma cell-free DNA for gastric cancer detection

A dual-gene panel of two fragments of methylated IRF4 and one of ZEB2 in plasma cell-free DNA for gastric cancer detection

Early detection is crucial for increasing the survival rate of gastric cancer (GC). We aimed to identify a methylated cell-free DNA (cfDNA) marker panel for detecting GC. The differentially methylated CpGs (DMCs) were selected from datasets of The Cancer Genome Atlas (TCGA) and Gene Expression Omnib...

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Bibliographic Details
Main Authors: Chunxiao Bu, Zhilong Wang, Xianping Lv, Yanteng Zhao
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Epigenetics
Subjects:
Gastric cancer detection
methylated DNA marker
cfDNA
plasma
real-time methylated-specific PCR
IRF4
Online Access:https://www.tandfonline.com/doi/10.1080/15592294.2024.2374988
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