New Hair Growth Cream Formulation with Cocoa Pod Peel (Theobroma cacao L.)

Our previous study verified that the waste skin of cocoa (Theobroma cacao L) fruit or waste cocoa pod husks had the efficacy to overcome hair loss or alopecia. This study aims to determine the formula and activity of hair cream of cocoa pod peel water fraction, which is effective in stimulating hair...

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Main Authors: Resmi Mustarichie, Aliya Nur Hasanah, Gofarana Wilar, Dolih Gozali, Nyi Mekar Saptarini
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1155/2022/2299725
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author Resmi Mustarichie
Aliya Nur Hasanah
Gofarana Wilar
Dolih Gozali
Nyi Mekar Saptarini
author_facet Resmi Mustarichie
Aliya Nur Hasanah
Gofarana Wilar
Dolih Gozali
Nyi Mekar Saptarini
author_sort Resmi Mustarichie
collection DOAJ
description Our previous study verified that the waste skin of cocoa (Theobroma cacao L) fruit or waste cocoa pod husks had the efficacy to overcome hair loss or alopecia. This study aims to determine the formula and activity of hair cream of cocoa pod peel water fraction, which is effective in stimulating hair growth. Activity testing uses the modified Tanaka method. The results showed that the cocoa husk wastewater fraction could be formulated into hair cream, but there were changes in viscosity and pH after the freeze-thaw test, but still within the allowed limit. The hair cream water fraction gel stimulated hair growth activity based on the hair length data with a significant difference in concentration of the preparation. The best activity in hair cream preparation was at 12.5% concentration. In addition, there were no signs of irritation to the rabbit’s skin where hair cream preparation was applied. The results of this study indicated that cocoa fruit peel cream can be used for antialopecia treatments.
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institution Kabale University
issn 1537-744X
language English
publishDate 2022-01-01
publisher Wiley
record_format Article
series The Scientific World Journal
spelling doaj-art-8d366f1270d8496dbecfdf50dbcc37982025-02-03T05:58:10ZengWileyThe Scientific World Journal1537-744X2022-01-01202210.1155/2022/2299725New Hair Growth Cream Formulation with Cocoa Pod Peel (Theobroma cacao L.)Resmi Mustarichie0Aliya Nur Hasanah1Gofarana Wilar2Dolih Gozali3Nyi Mekar Saptarini4Pharmaceutical Analysis and Medicinal Chemistry DepartmentPharmaceutical Analysis and Medicinal Chemistry DepartmentPharmacology and Clinical Pharmacy DepartmentPharmaceutical and Technological Pharmacy DepartmentPharmaceutical and Technological Pharmacy DepartmentOur previous study verified that the waste skin of cocoa (Theobroma cacao L) fruit or waste cocoa pod husks had the efficacy to overcome hair loss or alopecia. This study aims to determine the formula and activity of hair cream of cocoa pod peel water fraction, which is effective in stimulating hair growth. Activity testing uses the modified Tanaka method. The results showed that the cocoa husk wastewater fraction could be formulated into hair cream, but there were changes in viscosity and pH after the freeze-thaw test, but still within the allowed limit. The hair cream water fraction gel stimulated hair growth activity based on the hair length data with a significant difference in concentration of the preparation. The best activity in hair cream preparation was at 12.5% concentration. In addition, there were no signs of irritation to the rabbit’s skin where hair cream preparation was applied. The results of this study indicated that cocoa fruit peel cream can be used for antialopecia treatments.http://dx.doi.org/10.1155/2022/2299725
spellingShingle Resmi Mustarichie
Aliya Nur Hasanah
Gofarana Wilar
Dolih Gozali
Nyi Mekar Saptarini
New Hair Growth Cream Formulation with Cocoa Pod Peel (Theobroma cacao L.)
The Scientific World Journal
title New Hair Growth Cream Formulation with Cocoa Pod Peel (Theobroma cacao L.)
title_full New Hair Growth Cream Formulation with Cocoa Pod Peel (Theobroma cacao L.)
title_fullStr New Hair Growth Cream Formulation with Cocoa Pod Peel (Theobroma cacao L.)
title_full_unstemmed New Hair Growth Cream Formulation with Cocoa Pod Peel (Theobroma cacao L.)
title_short New Hair Growth Cream Formulation with Cocoa Pod Peel (Theobroma cacao L.)
title_sort new hair growth cream formulation with cocoa pod peel theobroma cacao l
url http://dx.doi.org/10.1155/2022/2299725
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