Metabolic intermediate acetyl phosphate modulates bacterial virulence via acetylation

Metabolic intermediate acetyl phosphate modulates bacterial virulence via acetylation

Accumulating evidence indicates that bacterial metabolism plays an important role in virulence. Acetyl phosphate (AcP), the high-energy intermediate of the phosphotransacetylase-acetate kinase pathway, is the major acetyl donor in E. coli. PhoP is an essential transcription factor for bacterial viru...

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Bibliographic Details
Main Authors: Jie Ren, Yu Sang, Ran Qin, Yang Su, Zhongli Cui, Zhiguo Mang, Hao Li, Shaoyong Lu, Jian Zhang, Sen Cheng, Xiaoyun Liu, Jixi Li, Jie Lu, Wenjuan Wu, Guo-Ping Zhao, Feng Shao, Yu-Feng Yao
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Emerging Microbes and Infections
Subjects:
Acetyl phosphate
acetylation
phosphorylation
PhoP
virulence
metabolism
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2018.1558963
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