Phenotypic alterations in articulating joint cells: Role of mechanically loaded MSC secretome

Phenotypic alterations in articulating joint cells: Role of mechanically loaded MSC secretome

Improvements in the treatment of cartilage require insights into the secretory profile of mesenchymal stem cells (MSCs). Apart from their differentiation potential, MSCs secrete a multitude of molecules with therapeutic properties that benefit chondrogenesis and immunomodulation. Previously, we empl...

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Bibliographic Details
Main Authors: Yann D. Ladner, Ursula Menzel, Keith Thompson, Angela R. Armiento, Martin J. Stoddart
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Heliyon
Subjects:
Secretome
Bioreactor
Mechanical loading
Tissue engineering
Cartilage
Mesenchymal stem cells
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844025006140
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