Refractory Infection of Mycobacterium abscessus: Skin and Soft Tissue Infection Recurred under Combination Therapy of Surgery and Outpatient Antibiotics

Mycobacterium abscessus (M. abscessus) is a nontuberculous mycobacterium that causes skin and soft tissue infections. Treatment methods for these infections, including the type and duration of antimicrobial agents, have not been established. The function of surgery is also unknown. We report a case...

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Main Authors: Atsuki Yamada, Ken Yukawa, Tomoaki Eguchi
Format: Article
Language:English
Published: Japan Society of Plastic and Reconstructive Surgery 2024-10-01
Series:Journal of Plastic and Reconstructive Surgery
Subjects:
Online Access:https://www.jstage.jst.go.jp/article/jprs/3/4/3_2023-0055/_pdf/-char/en
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author Atsuki Yamada
Ken Yukawa
Tomoaki Eguchi
author_facet Atsuki Yamada
Ken Yukawa
Tomoaki Eguchi
author_sort Atsuki Yamada
collection DOAJ
description Mycobacterium abscessus (M. abscessus) is a nontuberculous mycobacterium that causes skin and soft tissue infections. Treatment methods for these infections, including the type and duration of antimicrobial agents, have not been established. The function of surgery is also unknown. We report a case of skin and soft tissue infection of the left upper arm in a healthy 47-year-old Japanese man who was treated with complete surgical excision and antimicrobial therapy as feasible on an outpatient basis, which resulted in relapse <1 month later. Given the possibility of developing antibiotic-resistant bacteria, insufficient antimicrobial treatment should not be administered without careful consideration. There are currently few effective oral antimicrobial agents against M. abscessus, so careful antimicrobial therapy along with hospitalization (at least during the early treatment phase) is preferred, regardless of the use/nonuse of surgical treatment.
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publisher Japan Society of Plastic and Reconstructive Surgery
record_format Article
series Journal of Plastic and Reconstructive Surgery
spelling doaj-art-8d2104ea7e1d4b68aa5df43cd1da35742025-08-20T01:47:22ZengJapan Society of Plastic and Reconstructive SurgeryJournal of Plastic and Reconstructive Surgery2436-259X2024-10-01341681742023-0055Refractory Infection of Mycobacterium abscessus: Skin and Soft Tissue Infection Recurred under Combination Therapy of Surgery and Outpatient AntibioticsAtsuki Yamada0Ken Yukawa1Tomoaki Eguchi2Department of Plastic Surgery, Toranomon HospitalDepartment of Plastic Surgery, Toranomon HospitalDepartment of Plastic Surgery, Toranomon HospitalMycobacterium abscessus (M. abscessus) is a nontuberculous mycobacterium that causes skin and soft tissue infections. Treatment methods for these infections, including the type and duration of antimicrobial agents, have not been established. The function of surgery is also unknown. We report a case of skin and soft tissue infection of the left upper arm in a healthy 47-year-old Japanese man who was treated with complete surgical excision and antimicrobial therapy as feasible on an outpatient basis, which resulted in relapse <1 month later. Given the possibility of developing antibiotic-resistant bacteria, insufficient antimicrobial treatment should not be administered without careful consideration. There are currently few effective oral antimicrobial agents against M. abscessus, so careful antimicrobial therapy along with hospitalization (at least during the early treatment phase) is preferred, regardless of the use/nonuse of surgical treatment.https://www.jstage.jst.go.jp/article/jprs/3/4/3_2023-0055/_pdf/-char/enmycobacterium abscessusskin and soft tissue infectionsurgeryantibiotics
spellingShingle Atsuki Yamada
Ken Yukawa
Tomoaki Eguchi
Refractory Infection of Mycobacterium abscessus: Skin and Soft Tissue Infection Recurred under Combination Therapy of Surgery and Outpatient Antibiotics
Journal of Plastic and Reconstructive Surgery
mycobacterium abscessus
skin and soft tissue infection
surgery
antibiotics
title Refractory Infection of Mycobacterium abscessus: Skin and Soft Tissue Infection Recurred under Combination Therapy of Surgery and Outpatient Antibiotics
title_full Refractory Infection of Mycobacterium abscessus: Skin and Soft Tissue Infection Recurred under Combination Therapy of Surgery and Outpatient Antibiotics
title_fullStr Refractory Infection of Mycobacterium abscessus: Skin and Soft Tissue Infection Recurred under Combination Therapy of Surgery and Outpatient Antibiotics
title_full_unstemmed Refractory Infection of Mycobacterium abscessus: Skin and Soft Tissue Infection Recurred under Combination Therapy of Surgery and Outpatient Antibiotics
title_short Refractory Infection of Mycobacterium abscessus: Skin and Soft Tissue Infection Recurred under Combination Therapy of Surgery and Outpatient Antibiotics
title_sort refractory infection of mycobacterium abscessus skin and soft tissue infection recurred under combination therapy of surgery and outpatient antibiotics
topic mycobacterium abscessus
skin and soft tissue infection
surgery
antibiotics
url https://www.jstage.jst.go.jp/article/jprs/3/4/3_2023-0055/_pdf/-char/en
work_keys_str_mv AT atsukiyamada refractoryinfectionofmycobacteriumabscessusskinandsofttissueinfectionrecurredundercombinationtherapyofsurgeryandoutpatientantibiotics
AT kenyukawa refractoryinfectionofmycobacteriumabscessusskinandsofttissueinfectionrecurredundercombinationtherapyofsurgeryandoutpatientantibiotics
AT tomoakieguchi refractoryinfectionofmycobacteriumabscessusskinandsofttissueinfectionrecurredundercombinationtherapyofsurgeryandoutpatientantibiotics