Methotrexate and Tumor Necrosis Factor Inhibitors Independently Decrease Neutralizing Antibodies after SARS-CoV-2 Vaccination: Updated Results from the SUCCEED Study

Methotrexate and Tumor Necrosis Factor Inhibitors Independently Decrease Neutralizing Antibodies after SARS-CoV-2 Vaccination: Updated Results from the SUCCEED Study

<b>Objective:</b> SARS-CoV-2 remains the third most common cause of death in North America. We studied the effects of methotrexate and tumor necrosis factor inhibitor (TNFi) on neutralization responses after COVID-19 vaccination in immune-mediated inflammatory disease (IMID). <b>Me...

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Main Authors: Carol A Hitchon, Dawn M. E. Bowdish, Gilles Boire, Paul R. Fortin, Louis Flamand, Vinod Chandran, Roya M. Dayam, Anne-Claude Gingras, Catherine M. Card, Inés Colmegna, Maggie J. Larché, Gilaad G. Kaplan, Luck Lukusa, Jennifer L.F. Lee, Sasha Bernatsky, on behalf of the SUCCEED Investigative Team
Format: Article
Language:English
Published: MDPI AG 2024-09-01
Series:Vaccines
Subjects:
COVID-19
vaccination
immune-mediated inflammatory disease
methotrexate
tumor necrosis factor inhibitors
autoimmune diseases
Online Access:https://www.mdpi.com/2076-393X/12/9/1061
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