The genetic diversity and populational specificity of the human gut virome at single-nucleotide resolution

The genetic diversity and populational specificity of the human gut virome at single-nucleotide resolution

Abstract Background Large-scale characterization of gut viral genomes provides strain-resolved insights into host-microbe interactions. However, existing viral genomes are mainly derived from Western populations, limiting our understanding of global gut viral diversity and functional variations nece...

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Main Authors: Xiuchao Wang, Quanbin Dong, Pan Huang, Shuai Yang, Mengke Gao, Chengcheng Zhang, Chuan Zhang, Youpeng Deng, Zijing Huang, Beining Ma, Yuwen Jiao, Yan Zhou, Tingting Wu, Huayiyang Zou, Jing Shi, Yanhui Sheng, Yifeng Wang, CGVR Consortium, Liming Tang, Shixian Hu, Yi Duan, Wei Sun, Wei Chen, Qixiao Zhai, Xiangqing Kong, Lianmin Chen
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Microbiome
Subjects:
Virome
Metagenomics
Cohort study
Genomic epidemiology
Bioinformatics
Online Access:https://doi.org/10.1186/s40168-025-02185-9
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