Predicting individual treatment response in alcohol use disorders: a reverse translational proof-of-concept study
Abstract The development of medications for alcohol use disorders (AUD) faces stagnation, as promising drugs failed to translate in clinic. Screening on homogeneous groups of animals drugs later tested on heterogeneous clinical cohorts may contribute to the translational gap. We hypothesized that a...
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| Main Authors: | Sara De Carlo, Hela Mrizak, Andrea Della Valle, Veronica Lunerti, Manthoula O. Kyratzi, Alessandra Mammone, Antonio Lacorte, Adana Keshishian, Min Li, Esi Domi, Di Qin, Leah Solberg Woods, Laura Soverchia, Massimo Ubaldi, Roberto Ciccocioppo, Nazzareno Cannella |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2025-06-01
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| Series: | Translational Psychiatry |
| Online Access: | https://doi.org/10.1038/s41398-025-03431-2 |
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