Evaluating metabolome-wide causal effects on risk for psychiatric and neurodegenerative disorders
Abstract Background Evidence indicates phenotypic and biological overlap between psychiatric and neurodegenerative disorders. Further identification of underlying mutual and unique biological mechanisms may yield novel multi-disorder and disorder-specific therapeutic targets. The metabolome represen...
Saved in:
| Main Authors: | Lachlan Gilchrist, Julian Mutz, Pirro Hysi, Cristina Legido-Quigley, Sulev Kõks, Cathryn M. Lewis, Petroula Proitsi |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-06-01
|
| Series: | BMC Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12916-025-04129-4 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Statistical examination of shared loci in neuropsychiatric diseases using genome-wide association study summary statistics
by: Thomas P Spargo, et al.
Published: (2024-12-01) -
An unraveled mystery: What's the role of brain sphingolipids in neurodegenerative and psychiatric disorders
by: Xintian Bie, et al.
Published: (2025-04-01) -
Stress-Induced Sleep Dysregulation: The Roles of Astrocytes and Microglia in Neurodegenerative and Psychiatric Disorders
by: Ángel R. Rábago-Monzón, et al.
Published: (2025-05-01) -
Tracing Pharmaceuticals in Water Systems: Focus on Neurodegenerative and Psychiatric Treatments
by: Paula Paíga, et al.
Published: (2024-11-01) -
Metabolome-wide Mendelian randomisation reveals causal links between circulating metabolites and type 1 diabetesResearch in context
by: Basile Jumentier, et al.
Published: (2025-07-01)