Detection, Characterization, and Clinical Application of Mesenchymal Stem Cells in Periodontal Ligament Tissue
Mesenchymal stem cells (MSCs) are a kind of somatic stem cells that exert a potential to differentiate into multiple cell types and undergo robust clonal self-renewal; therefore, they are considered as a highly promising stem cell population for tissue engineering. MSCs are identified in various adu...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Stem Cells International |
| Online Access: | http://dx.doi.org/10.1155/2018/5450768 |
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| _version_ | 1832556560288579584 |
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| author | Atsushi Tomokiyo Shinichiro Yoshida Sayuri Hamano Daigaku Hasegawa Hideki Sugii Hidefumi Maeda |
| author_facet | Atsushi Tomokiyo Shinichiro Yoshida Sayuri Hamano Daigaku Hasegawa Hideki Sugii Hidefumi Maeda |
| author_sort | Atsushi Tomokiyo |
| collection | DOAJ |
| description | Mesenchymal stem cells (MSCs) are a kind of somatic stem cells that exert a potential to differentiate into multiple cell types and undergo robust clonal self-renewal; therefore, they are considered as a highly promising stem cell population for tissue engineering. MSCs are identified in various adult organs including dental tissues. Periodontal ligament (PDL) is a highly specialized connective tissue that surrounds the tooth root. PDL also contains MSC population, and many researchers have isolated them and performed their detailed characterization. Here, we review the current understanding of the features and functions of MSC population in PDL tissues and discuss their possibility for the application of PDL regeneration. |
| format | Article |
| id | doaj-art-8ca4808bde4e41a8a8934325f9399812 |
| institution | Kabale University |
| issn | 1687-966X 1687-9678 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Stem Cells International |
| spelling | doaj-art-8ca4808bde4e41a8a8934325f93998122025-02-03T05:45:08ZengWileyStem Cells International1687-966X1687-96782018-01-01201810.1155/2018/54507685450768Detection, Characterization, and Clinical Application of Mesenchymal Stem Cells in Periodontal Ligament TissueAtsushi Tomokiyo0Shinichiro Yoshida1Sayuri Hamano2Daigaku Hasegawa3Hideki Sugii4Hidefumi Maeda5Division of Endodontics, Kyushu University Hospital, Fukuoka, JapanDivision of Endodontics, Kyushu University Hospital, Fukuoka, JapanDepartment of Endodontology and Operative Dentistry, Faculty of Dental Science, Kyushu University, Fukuoka, JapanDivision of Endodontics, Kyushu University Hospital, Fukuoka, JapanDivision of Endodontics, Kyushu University Hospital, Fukuoka, JapanDivision of Endodontics, Kyushu University Hospital, Fukuoka, JapanMesenchymal stem cells (MSCs) are a kind of somatic stem cells that exert a potential to differentiate into multiple cell types and undergo robust clonal self-renewal; therefore, they are considered as a highly promising stem cell population for tissue engineering. MSCs are identified in various adult organs including dental tissues. Periodontal ligament (PDL) is a highly specialized connective tissue that surrounds the tooth root. PDL also contains MSC population, and many researchers have isolated them and performed their detailed characterization. Here, we review the current understanding of the features and functions of MSC population in PDL tissues and discuss their possibility for the application of PDL regeneration.http://dx.doi.org/10.1155/2018/5450768 |
| spellingShingle | Atsushi Tomokiyo Shinichiro Yoshida Sayuri Hamano Daigaku Hasegawa Hideki Sugii Hidefumi Maeda Detection, Characterization, and Clinical Application of Mesenchymal Stem Cells in Periodontal Ligament Tissue Stem Cells International |
| title | Detection, Characterization, and Clinical Application of Mesenchymal Stem Cells in Periodontal Ligament Tissue |
| title_full | Detection, Characterization, and Clinical Application of Mesenchymal Stem Cells in Periodontal Ligament Tissue |
| title_fullStr | Detection, Characterization, and Clinical Application of Mesenchymal Stem Cells in Periodontal Ligament Tissue |
| title_full_unstemmed | Detection, Characterization, and Clinical Application of Mesenchymal Stem Cells in Periodontal Ligament Tissue |
| title_short | Detection, Characterization, and Clinical Application of Mesenchymal Stem Cells in Periodontal Ligament Tissue |
| title_sort | detection characterization and clinical application of mesenchymal stem cells in periodontal ligament tissue |
| url | http://dx.doi.org/10.1155/2018/5450768 |
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