Effectiveness of a Web-Based Self-Guided Intervention (MINDxYOU) for Reducing Stress and Promoting Mental Health Among Health Professionals: Results From a Stepped-Wedge Cluster Randomized Trial

BackgroundThe high levels of sustained stress that health professionals often experience are a significant risk factor for developing mental health problems, such as anxiety, depression, and somatic symptoms, that not only affect their well-being but also have major social an...

Full description

Saved in:
Bibliographic Details
Main Authors: Yolanda López-del-Hoyo, Selene Fernández-Martínez, Adrian Perez-Aranda, Alicia Monreal-Bartolomé, Alberto Barceló-Soler, Loreto Camarero-Grados, Carilene Armas-Landaeta, José Guzmán-Parra, Vera Carbonell, Daniel Campos, Xinyuan Chen, Javier García-Campayo
Format: Article
Language:English
Published: JMIR Publications 2025-02-01
Series:Journal of Medical Internet Research
Online Access:https://www.jmir.org/2025/1/e59653
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832542834030280704
author Yolanda López-del-Hoyo
Selene Fernández-Martínez
Adrian Perez-Aranda
Alicia Monreal-Bartolomé
Alberto Barceló-Soler
Loreto Camarero-Grados
Carilene Armas-Landaeta
José Guzmán-Parra
Vera Carbonell
Daniel Campos
Xinyuan Chen
Javier García-Campayo
author_facet Yolanda López-del-Hoyo
Selene Fernández-Martínez
Adrian Perez-Aranda
Alicia Monreal-Bartolomé
Alberto Barceló-Soler
Loreto Camarero-Grados
Carilene Armas-Landaeta
José Guzmán-Parra
Vera Carbonell
Daniel Campos
Xinyuan Chen
Javier García-Campayo
author_sort Yolanda López-del-Hoyo
collection DOAJ
description BackgroundThe high levels of sustained stress that health professionals often experience are a significant risk factor for developing mental health problems, such as anxiety, depression, and somatic symptoms, that not only affect their well-being but also have major social and organizational consequences. Different interventions, including those based on third-wave psychotherapy principles (ie, mindfulness, compassion, and acceptance), have proven to be effective in reducing stress in this population. Among them, those delivered on the web constitute a promising alternative with notable advantages in accessibility and flexibility, but some adherence inconveniences may limit their efficacy. ObjectiveThis study aimed to evaluate the effectiveness of the MINDxYOU program, a web-based self-guided intervention based on third-wave psychotherapy principles, to reduce perceived stress and promote mental health in a sample of health professionals. MethodsIn a stepped-wedge cluster randomized design, 357 health professionals from health centers in Aragon and Málaga, Spain, were recruited. They were divided into 6 clusters—3 per region—and randomly assigned to 1 of the 3 sequences, each starting with a control phase and then transitioning to the intervention phase (the MINDxYOU program) after 8, 16, or 24 weeks. This self-guided, web-based program, designed to be completed over 8 weeks, included weekly contact (via WhatsApp, call, or email) from the research team to promote adherence. Participants were assessed on the web every 8 weeks for 5 assessments. Perceived stress was the study’s primary outcome, with additional measures of clinical factors (anxiety, depression, and somatization) and process variables (resilience, mindfulness, compassion, and acceptance). ResultsThe program was initiated by 229 participants, 112 (48.9%) of whom were completers (ie, completed at least 3 of the 4 modules). Perceived stress demonstrated a significant reduction both when considering the entire sample (β=–1.08, SE 0.51; P=.03) and the sample of completers (β=–1.84, SE 0.62; P=.003). The proportion of participants reflecting “low stress” increased after the treatment (n=90, 46.6% vs n=100, 28.8% at baseline). Intracluster analysis revealed that pre- versus postintervention moderate effects were present in 2 clusters (Cohen d=0.46 and 0.62), and these were maintained in subsequent assessments. The linear mixed-effects models also showed that depression, anxiety, and somatization, as well as resilience, self-compassion, and some mindfulness facets, experienced significant improvements (P<.05) when comparing the intervention and control phases. ConclusionsThe MINDxYOU program was effective in reducing perceived stress and promoting mental health, as well as increasing resilience, mindfulness facets, and self-compassion. These effects suggest that participants experienced a tangible improvement that could potentially enhance their well-being. Adherence to the intervention was moderate, while program use was notable compared to similar interventions. Finding ways to promote adherence to the intervention would contribute to increasing the effectiveness of this program. Trial RegistrationClinicalTrials.gov NCT05436717; https://clinicaltrials.gov/study/NCT05436717 International Registered Report Identifier (IRRID)RR2-10.1186/s12912-022-01089-5
format Article
id doaj-art-8ca43180e0d54fb6a4a029aa64103c90
institution Kabale University
issn 1438-8871
language English
publishDate 2025-02-01
publisher JMIR Publications
record_format Article
series Journal of Medical Internet Research
spelling doaj-art-8ca43180e0d54fb6a4a029aa64103c902025-02-03T14:30:35ZengJMIR PublicationsJournal of Medical Internet Research1438-88712025-02-0127e5965310.2196/59653Effectiveness of a Web-Based Self-Guided Intervention (MINDxYOU) for Reducing Stress and Promoting Mental Health Among Health Professionals: Results From a Stepped-Wedge Cluster Randomized TrialYolanda López-del-Hoyohttps://orcid.org/0000-0002-1690-4130Selene Fernández-Martínezhttps://orcid.org/0000-0002-4453-3912Adrian Perez-Arandahttps://orcid.org/0000-0002-1602-3413Alicia Monreal-Bartoloméhttps://orcid.org/0000-0003-2088-2007Alberto Barceló-Solerhttps://orcid.org/0000-0002-2116-9257Loreto Camarero-Gradoshttps://orcid.org/0009-0009-0106-7673Carilene Armas-Landaetahttps://orcid.org/0009-0003-7076-0996José Guzmán-Parrahttps://orcid.org/0000-0002-1463-6435Vera Carbonellhttps://orcid.org/0000-0002-2397-4276Daniel Camposhttps://orcid.org/0000-0001-9903-4064Xinyuan Chenhttps://orcid.org/0000-0002-6127-9602Javier García-Campayohttps://orcid.org/0000-0002-3797-4218 BackgroundThe high levels of sustained stress that health professionals often experience are a significant risk factor for developing mental health problems, such as anxiety, depression, and somatic symptoms, that not only affect their well-being but also have major social and organizational consequences. Different interventions, including those based on third-wave psychotherapy principles (ie, mindfulness, compassion, and acceptance), have proven to be effective in reducing stress in this population. Among them, those delivered on the web constitute a promising alternative with notable advantages in accessibility and flexibility, but some adherence inconveniences may limit their efficacy. ObjectiveThis study aimed to evaluate the effectiveness of the MINDxYOU program, a web-based self-guided intervention based on third-wave psychotherapy principles, to reduce perceived stress and promote mental health in a sample of health professionals. MethodsIn a stepped-wedge cluster randomized design, 357 health professionals from health centers in Aragon and Málaga, Spain, were recruited. They were divided into 6 clusters—3 per region—and randomly assigned to 1 of the 3 sequences, each starting with a control phase and then transitioning to the intervention phase (the MINDxYOU program) after 8, 16, or 24 weeks. This self-guided, web-based program, designed to be completed over 8 weeks, included weekly contact (via WhatsApp, call, or email) from the research team to promote adherence. Participants were assessed on the web every 8 weeks for 5 assessments. Perceived stress was the study’s primary outcome, with additional measures of clinical factors (anxiety, depression, and somatization) and process variables (resilience, mindfulness, compassion, and acceptance). ResultsThe program was initiated by 229 participants, 112 (48.9%) of whom were completers (ie, completed at least 3 of the 4 modules). Perceived stress demonstrated a significant reduction both when considering the entire sample (β=–1.08, SE 0.51; P=.03) and the sample of completers (β=–1.84, SE 0.62; P=.003). The proportion of participants reflecting “low stress” increased after the treatment (n=90, 46.6% vs n=100, 28.8% at baseline). Intracluster analysis revealed that pre- versus postintervention moderate effects were present in 2 clusters (Cohen d=0.46 and 0.62), and these were maintained in subsequent assessments. The linear mixed-effects models also showed that depression, anxiety, and somatization, as well as resilience, self-compassion, and some mindfulness facets, experienced significant improvements (P<.05) when comparing the intervention and control phases. ConclusionsThe MINDxYOU program was effective in reducing perceived stress and promoting mental health, as well as increasing resilience, mindfulness facets, and self-compassion. These effects suggest that participants experienced a tangible improvement that could potentially enhance their well-being. Adherence to the intervention was moderate, while program use was notable compared to similar interventions. Finding ways to promote adherence to the intervention would contribute to increasing the effectiveness of this program. Trial RegistrationClinicalTrials.gov NCT05436717; https://clinicaltrials.gov/study/NCT05436717 International Registered Report Identifier (IRRID)RR2-10.1186/s12912-022-01089-5https://www.jmir.org/2025/1/e59653
spellingShingle Yolanda López-del-Hoyo
Selene Fernández-Martínez
Adrian Perez-Aranda
Alicia Monreal-Bartolomé
Alberto Barceló-Soler
Loreto Camarero-Grados
Carilene Armas-Landaeta
José Guzmán-Parra
Vera Carbonell
Daniel Campos
Xinyuan Chen
Javier García-Campayo
Effectiveness of a Web-Based Self-Guided Intervention (MINDxYOU) for Reducing Stress and Promoting Mental Health Among Health Professionals: Results From a Stepped-Wedge Cluster Randomized Trial
Journal of Medical Internet Research
title Effectiveness of a Web-Based Self-Guided Intervention (MINDxYOU) for Reducing Stress and Promoting Mental Health Among Health Professionals: Results From a Stepped-Wedge Cluster Randomized Trial
title_full Effectiveness of a Web-Based Self-Guided Intervention (MINDxYOU) for Reducing Stress and Promoting Mental Health Among Health Professionals: Results From a Stepped-Wedge Cluster Randomized Trial
title_fullStr Effectiveness of a Web-Based Self-Guided Intervention (MINDxYOU) for Reducing Stress and Promoting Mental Health Among Health Professionals: Results From a Stepped-Wedge Cluster Randomized Trial
title_full_unstemmed Effectiveness of a Web-Based Self-Guided Intervention (MINDxYOU) for Reducing Stress and Promoting Mental Health Among Health Professionals: Results From a Stepped-Wedge Cluster Randomized Trial
title_short Effectiveness of a Web-Based Self-Guided Intervention (MINDxYOU) for Reducing Stress and Promoting Mental Health Among Health Professionals: Results From a Stepped-Wedge Cluster Randomized Trial
title_sort effectiveness of a web based self guided intervention mindxyou for reducing stress and promoting mental health among health professionals results from a stepped wedge cluster randomized trial
url https://www.jmir.org/2025/1/e59653
work_keys_str_mv AT yolandalopezdelhoyo effectivenessofawebbasedselfguidedinterventionmindxyouforreducingstressandpromotingmentalhealthamonghealthprofessionalsresultsfromasteppedwedgeclusterrandomizedtrial
AT selenefernandezmartinez effectivenessofawebbasedselfguidedinterventionmindxyouforreducingstressandpromotingmentalhealthamonghealthprofessionalsresultsfromasteppedwedgeclusterrandomizedtrial
AT adrianperezaranda effectivenessofawebbasedselfguidedinterventionmindxyouforreducingstressandpromotingmentalhealthamonghealthprofessionalsresultsfromasteppedwedgeclusterrandomizedtrial
AT aliciamonrealbartolome effectivenessofawebbasedselfguidedinterventionmindxyouforreducingstressandpromotingmentalhealthamonghealthprofessionalsresultsfromasteppedwedgeclusterrandomizedtrial
AT albertobarcelosoler effectivenessofawebbasedselfguidedinterventionmindxyouforreducingstressandpromotingmentalhealthamonghealthprofessionalsresultsfromasteppedwedgeclusterrandomizedtrial
AT loretocamarerogrados effectivenessofawebbasedselfguidedinterventionmindxyouforreducingstressandpromotingmentalhealthamonghealthprofessionalsresultsfromasteppedwedgeclusterrandomizedtrial
AT carilenearmaslandaeta effectivenessofawebbasedselfguidedinterventionmindxyouforreducingstressandpromotingmentalhealthamonghealthprofessionalsresultsfromasteppedwedgeclusterrandomizedtrial
AT joseguzmanparra effectivenessofawebbasedselfguidedinterventionmindxyouforreducingstressandpromotingmentalhealthamonghealthprofessionalsresultsfromasteppedwedgeclusterrandomizedtrial
AT veracarbonell effectivenessofawebbasedselfguidedinterventionmindxyouforreducingstressandpromotingmentalhealthamonghealthprofessionalsresultsfromasteppedwedgeclusterrandomizedtrial
AT danielcampos effectivenessofawebbasedselfguidedinterventionmindxyouforreducingstressandpromotingmentalhealthamonghealthprofessionalsresultsfromasteppedwedgeclusterrandomizedtrial
AT xinyuanchen effectivenessofawebbasedselfguidedinterventionmindxyouforreducingstressandpromotingmentalhealthamonghealthprofessionalsresultsfromasteppedwedgeclusterrandomizedtrial
AT javiergarciacampayo effectivenessofawebbasedselfguidedinterventionmindxyouforreducingstressandpromotingmentalhealthamonghealthprofessionalsresultsfromasteppedwedgeclusterrandomizedtrial